Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | Cheapest | ||||
| Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | Fastest | ||||
| Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | No tags |
Last refresh of the prices: Yesterday at 5:06 PM CST.
Get from Tupelo to New Orleans
The journey takes about 17 hours 40 minutes, and with fares starting at just R 1 647, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87413 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 647
Frequently asked questions about travelling from Tupelo to New Orleans by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Tupelo to New Orleans?
The cheapest bus tickets from Tupelo to New Orleans start at R 1 647. The average price for this route is around R 2 664. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Tupelo to New Orleans?
The average bus journey time from Tupelo to New Orleans is 17h 40m, covering a distance of 495 km. The fastest bus gets you there in 12h 15m and is operated by Greyhound.
Which bus companies service the Tupelo to New Orleans route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Tupelo to New Orleans?
The earliest bus departs from Tupelo to New Orleans at 05:35. And the latest bus departs at 23:15.
What are the CO₂ emissions for the bus trip from Tupelo to New Orleans?
A bus trip from Tupelo to New Orleans produces an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to New Orleans was searched and found on 09 Dec 2025 with a price of R 1 739To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to New Orleans as early as possible.
You can expect to pay from R 1 739 to R 3 548 for a bus ticket from Tupelo to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 739, which is on 2025-12-09.
