Bus from Siena to Rome: Tickets & Timetables

Next bus departures

Next departures from Siena to Rome on 1 April
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus Bus
Siena Train Station
Rome Tiburtina Bus StationCheapest
Flixbus Bus
Siena Train Station
Rome Tiburtina Bus StationFastest
MarinoBusBus
Siena Train Station
Rome Tiburtina Bus StationNo tags
ItabusBus
Siena Train Station
Rome Tiburtina Bus StationNo tags
TiemmeBus
Piazza Gramsci
Rome Fiumicino Airport (T3)No tags

Last refresh of the prices: Today at 1:56 PM CEST.

Compare 2 ways to travel from Siena to Rome

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Rome. The journey takes about 3 hours 5 minutes and with fares starting at just R 123, it presents an excellent value for a comfortable ride.

28bus per day
3h 5mAverage duration
187 kmDistance
5kgCO₂ emissions
Average priceR 123 - R 1 382Average duration3h 5m
5kg CO₂e
Average priceR 511 - R 543Average duration5h 19m
4kg CO₂e

Frequently asked questions about travelling from Siena to Rome by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Siena to Rome?

    The cheapest bus tickets from Siena to Rome start at R 123. The average price for this route is around R 277. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Siena to Rome?

    The average bus journey time from Siena to Rome is 3h 5m, covering a distance of 187 km. The fastest bus gets you there in 1h 45m and is operated by FlixBus.

  3. Which bus companies service the Siena to Rome route?

    Several major bus companies operate on this route with 28 buses available per day, including services from FlixBus, Itabus, Tiemme SpA, MarinoBus.

  4. What is the earliest and latest departure time for the bus from Siena to Rome?

    The earliest bus departs from Siena to Rome at 05:15. And the latest bus departs at 22:25.

  5. What are the CO₂ emissions for the bus trip from Siena to Rome?

    A bus trip from Siena to Rome produces an estimated 4.658125 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Siena to Rome?

    According to Busbud customers, the highest-rated bus company on this route is Tiemme SpA, with an average rating of 4.4 out of 5 stars based on 103 reviews.

  7. Which bus company has the best Wi-Fi from Siena to Rome?

    Based on reviews on Busbud, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.3.

  8. Which bus company offers the most punctual service from Siena to Rome?

    According to Busbud traveller reviews, the most punctual bus company on this route is Tiemme SpA, with a punctuality rating of 4.5 out of 5 stars.

  9. Which bus company has the cleanest buses from Siena to Rome?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tiemme SpA, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/03
R 166
30/03
R 144
Today
R 124
01/04
R 247
02/04
R 247
03/04
R 247
04/04
R 186
05/04
R 187
busbud logoThe cheapest trip from Siena to Rome was searched and found on 31 Mar 2026 with a price of R 124

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Rome as early as possible.

You can expect to pay from R 124 to R 1 285 for a bus ticket from Siena to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at R 186, which is on 2026-04-04.

Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Siena to Rome?

busbud logoThe Bus is the cheapest travel choice for this destination

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