Find coaches from Santa Maria, US to San Diego, CA, US

Previously seen journeys

Next departures from Santa Maria to San Diego on 16 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakBus
Nicholson Ave
Santa Fe DepotNo tags
FlixBusBus
Nicholson Ave
Downtown SD (Seaport)No tags
AmtrakBus
Nicholson Ave
Santa Fe DepotNo tags
AmtrakBus
Nicholson Ave
Santa Fe DepotNo tags
AmtrakBus
Nicholson Ave
Santa Fe DepotNo tags

Get from Santa Maria to San Diego

This route is served by bus only

The journey takes about 8 hours 55 minutes, and with fares starting at just R 1 420, it presents an excellent value for a comfortable ride.

1bus per day
8h 55mAverage duration
390 kmDistance
10kgCO₂ emissions

Frequently asked questions about travelling from Santa Maria, US to San Diego, CA, US by bus

  1. How much does a bus ticket from Santa Maria to San Diego cost?

    The bus ticket price from Santa Maria to San Diego starts at R 1 420. The best way to find cheap bus tickets from Santa Maria to San Diego is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Santa Maria to San Diego?

    The average travel time between Santa Maria and San Diego is around 8h 55m, although the fastest bus will take about 8h 55m. This is the time it takes to travel the 392 km that separates the two cities.

  3. How many daily bus connections are there between Santa Maria and San Diego?

    The number of buses from Santa Maria to San Diego can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Maria to San Diego by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Santa Maria to San Diego?

    When taking the bus from Santa Maria to San Diego, you can travel comfortably and safely with Amtrak, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
14/11
No data
15/11
R 1 351
Today
No data
17/11
No data
18/11
No data
19/11
No data
20/11
No data
21/11
No data
busbud logoThe cheapest trip from Santa Maria, US to San Diego, CA, US was searched and found on 15 Nov 2025 with a price of R 1 351

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria, US to San Diego, CA, US as early as possible.

People from around the world trust Busbud

‌

Popular Buses Connecting Santa Maria

Buses Leaving from Santa Maria

Buses Going to Santa Maria

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego