- Panama City to Knoxville buses
Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Panama City Beach Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Panama City Beach Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Panama City Beach Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Panama City Beach Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Panama City Beach Station | Knoxville Bus Station | No tags |
Get from Panama City to Knoxville
The journey takes about 23 hours 10 minutes, and with fares starting at just R 3 050, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Knoxville?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87412 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 3 050
Frequently asked questions about travelling from Panama City, US to Knoxville, TN by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Panama City to Knoxville?
The cheapest bus tickets from Panama City to Knoxville start at R 3 050. The average price for this route is around R 3 050. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Panama City to Knoxville?
The average bus journey time from Panama City to Knoxville is 23h 10m, covering a distance of 670 km. The fastest bus gets you there in 23h 10m and is operated by Greyhound.
Which bus companies service the Panama City to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Panama City to Knoxville?
The earliest bus departs from Panama City to Knoxville at 21:40. And the latest bus departs at 21:40.
What are the CO₂ emissions for the bus trip from Panama City to Knoxville?
A bus trip from Panama City to Knoxville produces an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.






