Find coaches from Louisville to Chicago

Next departures

Next departures from Louisville to Chicago on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Louisville, KY
Chicago 95Th & Dan RyanCheapestFastest
Amtrak
Louisville, KY
Chicago (Union Station), ILNo tags
Greyhound Lines, Inc.
Louisville, KY
Downtown Greyhound StationNo tags
FlixBus
Louisville, KY
Downtown Greyhound StationNo tags
Greyhound Lines, Inc. + FlixBus
Louisville, KY
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Today at 8:03 AM EDT.

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Get from Louisville to Chicago

busbud logoThis route is served by bus only

The journey takes about 6 hours 40 minutes, and with fares starting at just US$38, it presents an excellent value for a comfortable ride.

18bus per day
6h 40mAverage duration
418 kmDistance
10kgCO₂ emissions

Bus Louisville to Chicago: Trip Overview

Average ticket priceUS$56
Average bus trip duration6h 40m
Number of daily buses18
Earliest bus departure01:50
Distance417 km
Latest bus departure19:30

Louisville to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Louisville to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Louisville to Chicago.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Louisville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Louisville - Chicago

  1. How much does a bus ticket from Louisville to Chicago cost?

    The bus ticket price from Louisville to Chicago starts at US$38. The best way to find cheap bus tickets from Louisville to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Louisville to Chicago?

    The average travel time between Louisville and Chicago is around 6h 40m, although the fastest bus will take about 5h 20m. This is the time it takes to travel the 432 km that separates the two cities.

  3. How many daily bus connections are there between Louisville and Chicago?

    The number of buses from Louisville to Chicago can differ depending on the day of the week. On average, there are 18 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Louisville to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Louisville to Chicago?

    When taking the bus from Louisville to Chicago, you can travel comfortably and safely with Greyhound, FlixBus, Amtrak.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$47
29/10
US$47
Today
US$57
31/10
US$53
01/11
US$50
02/11
US$45
03/11
US$46
04/11
US$41
busbud logoThe cheapest trip from Louisville to Chicago was searched and found on 04 Nov 2025 with a price of US$41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago as early as possible.

You can expect to pay from US$41 to US$134 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$41, which is on 2025-11-04.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Louisville to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Louisville to Chicago.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Louisville to Chicago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Louisville to Chicago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Louisville by bus?

Bus from Chicago to Louisville

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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