Find coaches from Jacksonville, FL to Charleston, SC, US

Next departures

Next departures from Jacksonville to Charleston on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Jacksonville Bus Station
4565 Gaynor Ave, North CharlestonCheapestFastest
FlixBus
Jacksonville Bus Station
4565 Gaynor Ave, North CharlestonNo tags

Last refresh of the prices: Yesterday at 10:09 PM EDT.

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Compare 3 ways to travel from Jacksonville to Charleston

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Charleston. The journey takes about 5 hours 5 minutes and with fares starting at just US$26, it presents an excellent value for a comfortable ride.

1bus per day
5h 5mAverage duration
325 kmDistance
8kgCO₂ emissions
Bus
Average priceUS$26 - US$70Average duration5h 5m
8kg CO₂e
Train
Average priceUS$51 - US$117Average duration10h 35m
29kg CO₂e
Shuttle
Average priceUS$91 - US$91Average duration5h
9kg CO₂e

Bus Jacksonville, FL to Charleston, SC, US: Trip Overview

Average ticket priceUS$41
Average bus trip duration5h 5m
Number of daily buses1
Earliest bus departure08:45
Distance324 km
Latest bus departure09:05

Jacksonville to Charleston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Charleston.

We make sure you can find a bus service from Jacksonville to Charleston from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Charleston from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Jacksonville, FL - Charleston, SC, US

  1. How much does a bus ticket from Jacksonville to Charleston cost?

    The bus ticket price from Jacksonville to Charleston starts at US$26. The best way to find cheap bus tickets from Jacksonville to Charleston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Jacksonville to Charleston?

    The average travel time between Jacksonville and Charleston is around 5h 5m, although the fastest bus will take about 4h 45m. This is the time it takes to travel the 318 km that separates the two cities.

  3. How many daily bus connections are there between Jacksonville and Charleston?

    The number of buses from Jacksonville to Charleston can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Jacksonville to Charleston by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Jacksonville to Charleston?

    When taking the bus from Jacksonville to Charleston, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Jacksonville to Charleston?

    Buses travelling between Jacksonville and Charleston leave from Jacksonville Amtrak Station or W Forsyth St and arrive at Charleston Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$40
29/10
US$37
Today
US$44
31/10
US$37
01/11
US$27
02/11
US$36
03/11
US$21
04/11
US$19
busbud logoThe cheapest trip from Jacksonville, FL to Charleston, SC, US was searched and found on 04 Nov 2025 with a price of US$19

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Charleston, SC, US as early as possible.

You can expect to pay from US$19 to US$57 for a bus ticket from Jacksonville, FL to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$19, which is on 2025-11-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Charleston, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Jacksonville to Charleston.

Make a music playlist for your bus ride from Jacksonville to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Jacksonville, FL to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Charleston, SC, US to Jacksonville, FL

You can also go to Charleston, SC, US by train

Train from Jacksonville, FL to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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