Find coaches from Charleston, SC, US to Jacksonville, FL

Next departures

Next departures from Charleston to Jacksonville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
4565 Gaynor Ave, North Charleston
Jacksonville Bus StationCheapestFastest

Last refresh of the prices: Yesterday at 8:33 PM EDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Charleston to Jacksonville

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 5 hours 5 minutes and with fares starting at just US$40, it presents an excellent value for a comfortable ride.

1bus per day
5h 5mAverage duration
325 kmDistance
8kgCO₂ emissions
Bus
Average priceUS$40 - US$64Average duration5h 5m
8kg CO₂e
Train
Average priceUS$51 - US$153Average duration5h 28m
29kg CO₂e

Bus Charleston, SC, US to Jacksonville, FL: Trip Overview

Average ticket priceUS$45
Average bus trip duration5h 5m
Number of daily buses1
Earliest bus departure15:15
Distance324 km

Charleston to Jacksonville Bus

Busbud helps you find a bus from Charleston to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Charleston to Jacksonville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Charleston to Jacksonville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Charleston, SC, US - Jacksonville, FL

  1. How much does a bus ticket from Charleston to Jacksonville cost?

    The bus ticket price from Charleston to Jacksonville starts at US$40. The best way to find cheap bus tickets from Charleston to Jacksonville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Charleston to Jacksonville?

    The average travel time between Charleston and Jacksonville is around 5h 5m, although the fastest bus will take about 5h 5m. This is the time it takes to travel the 318 km that separates the two cities.

  3. How many daily bus connections are there between Charleston and Jacksonville?

    The number of buses from Charleston to Jacksonville can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Charleston to Jacksonville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Charleston to Jacksonville?

    When taking the bus from Charleston to Jacksonville, you can travel comfortably and safely with FlixBus, Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$37
29/10
US$37
Today
US$36
31/10
US$38
01/11
US$35
02/11
US$36
03/11
US$34
04/11
US$33
busbud logoThe cheapest trip from Charleston, SC, US to Jacksonville, FL was searched and found on 04 Nov 2025 with a price of US$33

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Jacksonville, FL as early as possible.

You can expect to pay from US$33 to US$38 for a bus ticket from Charleston, SC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at US$33, which is on 2025-11-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Charleston and Jacksonville!

Much more than a mere vehicle taking you from Charleston to Jacksonville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charleston to Jacksonville that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Charleston to Jacksonville while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Charleston, SC, US to Jacksonville, FL?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charleston, SC, US by bus?

Bus from Jacksonville, FL to Charleston, SC, US

You can also go to Jacksonville, FL by train

Train from Charleston, SC, US to Jacksonville, FL

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Charleston

Buses Leaving from Charleston

Buses Going to Charleston

Popular Buses Connecting Jacksonville

Buses Leaving from Jacksonville

Buses Going to Jacksonville