Find coaches from Greenville, SC to Boston, MA, US

Next bus departures

Next departures from Greenville to Boston on 18 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
1116 Woodruff Rd
BrooklineCheapest
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
Boston (South Station)Fastest
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
Boston (South Station)No tags
Greyhound Lines, Inc. + FlixBus
Bus
1116 Woodruff Rd
BrooklineNo tags
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
Boston (South Station)No tags

Last refresh of the prices: Last Tuesday at 12:04 AM EST.

Compare 2 ways to travel from Greenville to Boston

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 22 hours 55 minutes and with fares starting at just R 1 424, it presents an excellent value for a comfortable ride.

8bus per day
22h 55mAverage duration
1285 kmDistance
32kgCO₂ emissions
Bus
Average priceR 1 424 - R 4 582Average duration22h 55m
32kg CO₂e
Train
Average priceR 2 763 - R 22 591Average duration20h 44m
117kg CO₂e

Frequently asked questions about travelling from Greenville, SC to Boston, MA, US by bus

  1. How much does a bus ticket from Greenville to Boston cost?

    The bus ticket price from Greenville to Boston starts at R 1 424. The best way to find cheap bus tickets from Greenville to Boston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Greenville to Boston?

    The average travel time between Greenville and Boston is around 22h 55m, although the fastest bus will take about 20h 30m. This is the time it takes to travel the 1291 km that separates the two cities.

  3. How many daily bus connections are there between Greenville and Boston?

    The number of buses from Greenville to Boston can differ depending on the day of the week. On average, there are 8 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Greenville to Boston by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Greenville to Boston?

    When taking the bus from Greenville to Boston, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Greenville to Boston?

    Buses travelling between Greenville and Boston leave from Guadalajara Supermarket Bus Stop or Greenville Bus Station and arrive at Back Bay Station, North Station, South Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
14/11
R 2 947
15/11
R 2 061
Today
R 2 017
17/11
R 1 798
18/11
R 1 842
19/11
R 1 649
20/11
R 2 351
21/11
R 3 018
busbud logoThe cheapest trip from Greenville, SC to Boston, MA, US was searched and found on 19 Nov 2025 with a price of R 1 649

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Boston, MA, US as early as possible.

You can expect to pay from R 1 649 to R 3 824 for a bus ticket from Greenville, SC to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 649, which is on 2025-11-19.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Greenville, SC to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

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