Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | UCSD Health La Jolla Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | UCSD Health La Jolla Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | San Diego (Old Town-FlixBus) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | Downtown SD (Seaport) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | San Diego (Old Town-FlixBus) | No tags |
Last refresh of the prices: Last Wednesday at 12:56 AM EST.
Compare 2 ways to travel from Boston to San Diego
Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 3 days, 11 hours 10 minutes and with fares starting at just R 2 460, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and San Diego?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Frequently asked questions about travelling from Boston, MA, US to San Diego, CA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Boston to San Diego?
The cheapest bus tickets from Boston to San Diego start at R 2 460. The average price for this route is around R 8 563. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Boston to San Diego?
The average bus journey time from Boston to San Diego is 3d 11h, covering a distance of 4147 km. The fastest bus gets you there in 3d 1h and is operated by Greyhound.
Which bus companies service the Boston to San Diego route?
What is the earliest and latest departure time for the bus from Boston to San Diego?
The earliest bus departs from Boston to San Diego at 01:30. And the latest bus departs at 20:55.
What are the CO₂ emissions for the bus trip from Boston to San Diego?
A bus trip from Boston to San Diego produces an estimated 104 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Boston to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Boston to San Diego?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Boston to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to San Diego, CA, US was searched and found on 06 Dec 2025 with a price of R 5 825To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to San Diego, CA, US as early as possible.
You can expect to pay from R 5 825 to R 10 834 for a bus ticket from Boston, MA, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 5 825, which is on 2025-12-06.
What's the cheapest way to go from Boston, MA, US to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
