Trains leaving Friday
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 15 August atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: 17 August atDestination city: GreenvilleDestination location: Greenville StationOperated by: Amtrak
Vehicle: TrainDuration: - Departure time: 15 August atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: 17 August atDestination city: GreenvilleDestination location: Greenville StationOperated by: AmtrakVehicle: TrainDuration:
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Compare 2 ways to travel from Chicago to Greenville
Busbud recommends taking the bus from Chicago to GreenvilleAmong the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 20 hours 50 minutes and with fares starting at just US$76, it presents an excellent value for a comfortable ride.
Train Chicago to Greenville, SC: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5383 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$217
Chicago to Greenville Train
Busbud helps you find a train from Chicago to Greenville. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
We make sure you can find a train service from Chicago to Greenville from the most reliable train companies operating this trip.
From train tickets to high-end trains trip from Chicago to Greenville, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip Chicago - Greenville, SC
How much does a cheap train ticket from Chicago to Greenville cost?
The average train ticket price from Chicago to Greenville is US$385. The best way to find cheap train tickets from Chicago to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Chicago to Greenville?
A train trip between Chicago and Greenville is around 1d 9h, although the fastest train will take about 1d 9h. This is the time it takes to travel the 561 miles that separates the two cities.
How many daily train are there between Chicago and Greenville?
The number of trains from Chicago to Greenville can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Chicago to Greenville by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Chicago to Greenville?
When taking the train from Chicago to Greenville, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Greenville, SC was searched and found on 9 Aug 2025 with a price of US$208To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to Greenville, SC as early as possible.
You can expect to pay from US$208 to US$1,427 for a train ticket from Chicago to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$269, which is on 2025-08-13.
About Train Travel
Train Travel Tips
There are many train stations in the world, explore station pages on Busbud to get all information you need.
Regional train? High-speed train? Whichever train to Greenville you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Chicago and Greenville compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Make a music playlist for your train ride from Chicago to Greenville and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Japanese trains are always on time. It is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologise to each passenger.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60m under the Great Wall of China!
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Top Travelled Train Routes
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