Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Pittsburgh Intermodal Station | Downtown Greyhound Station | Cheapest | ||||
| Bus | Pittsburgh Intermodal Station | Downtown Greyhound Station | Fastest | ||||
| Bus | Pittsburgh Intermodal Station | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Pittsburgh Intermodal Station | Chicago 95Th & Dan Ryan | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Downtown Greyhound Station | No tags |
Last refresh of the prices: Yesterday at 18:20 EST.
Compare 2 ways to travel from Pittsburgh to Chicago
Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 9 hours 46 minutes and with fares starting at just £40, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and Chicago?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling by bus from Pittsburgh to Chicago
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Pittsburgh to Chicago?
The cheapest coach tickets from Pittsburgh to Chicago start from £41. The average price for this route is around £54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Pittsburgh to Chicago?
The average bus journey time from Pittsburgh to Chicago is 13h 25m, covering a distance of 410 miles. The fastest bus can take you there in 10h 5m and is operated by Greyhound.
Which bus companies service the Pittsburgh to Chicago route?
What is the earliest and latest departure time for the bus from Pittsburgh to Chicago?
The earliest bus departs from Pittsburgh to Chicago at 00:40. And the latest bus departs at 20:00.
What are the CO₂ emissions for the bus trip from Pittsburgh to Chicago?
A bus journey from Pittsburgh to Chicago produces an estimated 16 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Pittsburgh to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87523 reviews.
Which company has the best Wi-Fi from Pittsburgh to Chicago?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Pittsburgh to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Pittsburgh to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Chicago was searched and found on 25 Feb 2026 with a price of £46To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Chicago as early as possible.
You can expect to pay from £46 to £130 for a bus ticket from Pittsburgh to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £46, which is on 2026-02-25.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
