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Compare 3 ways to travel from Mainz to Lyon

Bus
Average priceUS$51 - US$154Average duration15h 20m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$60 - US$109Average duration17h 21m
13kg CO₂e5 out of 5 stars
Carpool
Average priceUS$55 - US$55Average duration7h 40m
22kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Mainz to Lyon

Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 7 hours 40 minutes and with fares starting at just US$55, it presents an excellent value for a comfortable ride.

1carpool per day
7h 40mAverage duration
US$55Cheapest ticket
22kgCO₂ emissions

Bus Mainz to Lyon: Trip Overview

Average ticket priceUS$88
Average bus trip duration15h 20m
Number of daily buses9
Earliest bus departure04:30
Distance330 miles
Latest bus departure22:40

Mainz to Lyon Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mainz to Lyon.

Bus service from Mainz to Lyon will be provided by the most trusted bus companies.

Discover how much the bus trip from Mainz to Lyon will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Mainz - Lyon

  1. What's the distance between Mainz and Lyon by coach?

    The journey from Mainz to Lyon by coach covers an approximate distance of 333 miles (537 km).

  2. How can I travel from Mainz to Lyon avoiding air travel?

    To travel from Mainz to Lyon without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/08
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06/08
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Today
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08/08
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09/08
US$48
10/08
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busbud logoThe cheapest trip from Mainz to Lyon was searched and found on 9 Aug 2025 with a price of US$48

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Lyon as early as possible.

You can expect to pay from US$48 to US$150 for a bus ticket from Mainz to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at US$48, which is on 2025-08-09.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mainz to Lyon but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Mainz to Lyon, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Mainz to Lyon will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Mainz to Lyon while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Mainz by bus?

Bus from Mainz to Lyon

You can also go to Lyon by train

Train from Mainz to Lyon

Why choose Busbud?

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