Find coaches from Harrisburg to San Diego, CA, US

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Tomorrow9 Aug
from US$344
Sun10 Aug
Mon11 Aug
Tue12 Aug
Wed13 Aug
Thu14 Aug
Fri15 Aug
Sat16 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 9 August at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 12 August at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 9 August at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 11 August at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 11 August at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 11 August at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 12 August at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Harrisburg to San Diego

Average priceUS$301 - US$380Average duration2d 23h
92kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average priceUS$461 - US$506Average duration3d 1h
334kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Harrisburg to San Diego

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 23 hours 10 minutes and with fares starting at just US$301, it presents an excellent value for a comfortable ride.

18bus per day
2d 23hAverage duration
US$301Cheapest ticket
92kgCO₂ emissions

Bus Harrisburg to San Diego, CA, US: Trip Overview

Average ticket priceUS$326
Average bus trip duration2d 23h
Number of daily buses18
Earliest bus departure02:30
Distance2273 miles
Latest bus departure21:10

Harrisburg to San Diego Bus

With Busbud, comparing and booking tickets for a bus from Harrisburg to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Harrisburg to San Diego will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Harrisburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Harrisburg - San Diego, CA, US

  1. How far is San Diego from Harrisburg by coach?

    The distance between Harrisburg and San Diego by coach is approximately 2275 miles (3668 km).

  2. Is there a way to reach San Diego from Harrisburg without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/08
No data
07/08
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Today
No data
09/08
US$336
10/08
No data
11/08
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12/08
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13/08
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busbud logoThe cheapest trip from Harrisburg to San Diego, CA, US was searched and found on 9 Aug 2025 with a price of US$336

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to San Diego, CA, US as early as possible.

You can expect to pay from US$336 to US$496 for a bus ticket from Harrisburg to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$336, which is on 2025-08-09.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Harrisburg to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Harrisburg to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Harrisburg to San Diego.

Make a music playlist for your bus ride from Harrisburg to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Harrisburg to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Harrisburg to San Diego, CA, US

You can also go to San Diego, CA, US by train

Train from Harrisburg to San Diego, CA, US

Why choose Busbud?

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