Find coaches from San Diego, CA, US to Lafayette, IN

Find affordable coach tickets from San Diego, CA, US to Lafayette, IN with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen journeys

One passenger / one way

  • Departure time: 9 September at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: 11 September at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 9 September at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: 12 September at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 9 September at
    Departure city: San Diego
    Departure location: Downtown SD (Seaport)
    Arrival time: 11 September at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 9 September at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: 11 September at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 9 September at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: 12 September at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus San Diego, CA, US to Lafayette, IN: Trip Overview

Average ticket priceUS$255
Average bus trip duration2d 7h
Number of daily buses7
Earliest bus departure06:45
Distance1750 miles
Latest bus departure19:35

San Diego to Lafayette Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Lafayette is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to Lafayette from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Diego to Lafayette, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego, CA, US - Lafayette, IN

  1. What's the distance between San Diego and Lafayette by coach?

    The distance between San Diego and Lafayette by coach is approximately 1755 miles (2831 km).

  2. How can I travel from San Diego to Lafayette avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/09
No data
09/09
US$225
Today
No data
11/09
No data
12/09
No data
13/09
No data
14/09
No data
15/09
No data
busbud logoThe cheapest trip from San Diego, CA, US to Lafayette, IN was searched and found on 9 Sept 2025 with a price of US$225

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Lafayette, IN as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Lafayette.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Lafayette, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Lafayette that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Lafayette.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to San Diego, CA, US by bus?

Bus from Lafayette, IN to San Diego, CA, US

You can also go to Lafayette, IN by train

Train from San Diego, CA, US to Lafayette, IN

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego

Popular Buses Connecting Lafayette

Buses Leaving from Lafayette

Buses Going to Lafayette