Find coaches from Greenville, SC to Florence, SC, US

Next departures

Next departures from Greenville to Florence on 3 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
1116 Woodruff Rd
Florence, SCCheapestFastest
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Bus stationNo tags

Last refresh of the prices: Yesterday at 18:49 EDT.

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Compare 2 ways to travel from Greenville to Florence

Bus
Average priceUS$52 - US$60Average duration14h 45m
6kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$433 - US$515Average duration1d
23kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Florence

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 14 hours 45 minutes and with fares starting at just US$52, it presents an excellent value for a comfortable ride.

2bus per day
14h 45mAverage duration
US$52Cheapest ticket
6kgCO₂ emissions

Bus Greenville, SC to Florence, SC, US: Trip Overview

Average ticket priceUS$55
Average bus trip duration14h 45m
Number of daily buses2
Earliest bus departure08:40
Distance151 miles
Latest bus departure22:00

Greenville to Florence Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Florence.

We make sure you can find a bus service from Greenville to Florence from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Greenville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Greenville, SC - Florence, SC, US

  1. What's the distance between Greenville and Florence by coach?

    The distance between Greenville and Florence by coach is approximately 163 miles (263 km).

  2. How can I get from Greenville to Florence without driving?

    You can travel to Florence from Greenville by coach, which provides a smooth ride and an affordable and convenient trip. You can also consider rideshare services depending on your preferences.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$66
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busbud logoThe cheapest trip from Greenville, SC to Florence, SC, US was searched and found on 3 Oct 2025 with a price of US$66

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Florence, SC, US as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Florence but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Florence, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Greenville to Florence.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Greenville, SC to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Florence, SC, US to Greenville, SC

You can also go to Florence, SC, US by train

Train from Greenville, SC to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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