Find coaches from Greenville, SC to Cincinnati

Next departures

Next departures from Greenville to Cincinnati on 3 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Cincinnati Bus StationCheapestFastest

Last refresh of the prices: Yesterday at 10:30 EDT.

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Compare 2 ways to travel from Greenville to Cincinnati

Bus
Average priceUS$73 - US$163Average duration12h 40m
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$165 - US$761Average duration23h 8m
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Cincinnati

Among the sustainable travel choices, the bus stands out as a good way to reach Cincinnati. The journey takes about 12 hours 40 minutes and with fares starting at just US$73, it presents an excellent value for a comfortable ride.

1bus per day
12h 40mAverage duration
US$73Cheapest ticket
13kgCO₂ emissions

Bus Greenville, SC to Cincinnati: Trip Overview

Average ticket priceUS$84
Average bus trip duration12h 40m
Number of daily buses1
Earliest bus departure14:45
Distance325 miles
Latest bus departure19:45

Greenville to Cincinnati Bus

Busbud helps you find a bus from Greenville to Cincinnati. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Greenville to Cincinnati from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Cincinnati will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Cincinnati

  1. What's the distance between Greenville and Cincinnati by coach?

    The distance between Greenville and Cincinnati by coach is approximately 319 miles (514 km).

  2. How can I travel from Greenville to Cincinnati avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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Today
US$206
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busbud logoThe cheapest trip from Greenville, SC to Cincinnati was searched and found on 3 Oct 2025 with a price of US$206

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Cincinnati as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Cincinnati!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Cincinnati, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Cincinnati will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Cincinnati while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Greenville, SC to Cincinnati?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Cincinnati to Greenville, SC

You can also go to Cincinnati by train

Train from Greenville, SC to Cincinnati

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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