Find coaches from Charleston, SC, US to Fort Myers

Find affordable coach tickets from Charleston, SC, US to Fort Myers with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen journeys

One passenger / one way

  • Departure time: 13 September at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: 14 September at
    Destination city: Fort Myers
    Destination location: Ft Myers Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 24 October at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: 25 October at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 21 December at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: 22 December at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 16 July at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: 17 July at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 19 July at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: 20 July at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Charleston to Fort Myers

Bus
Average priceUS$70 - US$100Average duration19h 5m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$129 - US$251Average duration14h 19m
64kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Charleston to Fort Myers

Among the sustainable travel choices, the bus stands out as a good way to reach Fort Myers. The journey takes about 19 hours 5 minutes and with fares starting at just US$70, it presents an excellent value for a comfortable ride.

1bus per day
19h 5mAverage duration
US$70Cheapest ticket
18kgCO₂ emissions

Bus Charleston, SC, US to Fort Myers: Trip Overview

Average ticket priceUS$79
Average bus trip duration19h 5m
Number of daily buses1
Earliest bus departure15:15
Distance444 miles

Charleston to Fort Myers Bus

Busbud helps you find a bus from Charleston to Fort Myers. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Charleston to Fort Myers will be provided by the most trusted bus companies.

Discover how much the bus trip from Charleston to Fort Myers will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Charleston, SC, US - Fort Myers

  1. How far is Fort Myers from Charleston by coach?

    The journey from Charleston to Fort Myers by coach covers an approximate distance of 441 miles (711 km).

  2. Is there a way to reach Fort Myers from Charleston without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/08
No data
31/08
No data
Today
No data
02/09
No data
03/09
No data
04/09
No data
05/09
No data
06/09
US$63
busbud logoThe cheapest trip from Charleston, SC, US to Fort Myers was searched and found on 6 Sept 2025 with a price of US$63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Fort Myers as early as possible.

You can expect to pay from US$63 to US$63 for a bus ticket from Charleston, SC, US to Fort Myers based on the last 2 days. You can expect to find the cheapest price for the trip at US$63, which is on 2025-09-06.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Charleston and Fort Myers!

Much more than a mere vehicle taking you from Charleston to Fort Myers, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Charleston to Fort Myers will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Charleston to Fort Myers.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Charleston, SC, US to Fort Myers?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charleston, SC, US by bus?

Bus from Fort Myers to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Charleston

Buses Leaving from Charleston

Buses Going to Charleston

Popular Buses Connecting Fort Myers

Buses Leaving from Fort Myers

Buses Going to Fort Myers