How much does a cheap train ticket from Syracuse to St. Louis cost?

The average train ticket price from Syracuse to St. Louis is $379. The best way to find cheap train tickets from Syracuse to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the trip from Syracuse to St. Louis?

A train trip between Syracuse and St. Louis is around 22h 2m, although the fastest train will take about 22h 2m. This is the time it takes to travel the 1280 km that separates the two cities.

How many daily trains are there between Syracuse and St. Louis?

The number of trains from Syracuse to St. Louis can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Syracuse to St. Louis by comparing and selecting the train that fits your travel style and budget on Busbud.

Which train companies travel from Syracuse to St. Louis?

When taking the train from Syracuse to St. Louis, you can travel comfortably and safely with Amtrak.

What are the departure and arrival stations for a train from Syracuse to St. Louis?

Trains travelling between Syracuse and St. Louis leave from Regional Transportation Center or Syracuse Airport and arrive at Gateway Station.

Train Syracuse to St. Louis from $212 | Refundable Tickets

Next train departures

Next departures for Syracuse to St. Louis on November 10
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	Cheapest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	Fastest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags

Next departures for Syracuse to St. Louis on November 11
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	Cheapest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	Fastest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags

Next departures for Syracuse to St. Louis on November 12
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	Cheapest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	Fastest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags

Next departures for Syracuse to St. Louis on November 14
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	CheapestFastest
Train	10:05pm	Amtrak Station	22h 2m	7:07pm	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags
Train	10:05pm	Amtrak Station	1d 3h	12:09am	Gateway Station	No tags

Last refresh of the prices: Last Thursday at 12:14 PM EST.

Compare 2 ways to go from Syracuse to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 22 hours 2 minutes, and with fares starting at just $272, it presents an excellent value for a comfortable ride.

1train per day

22h 2mAverage Duration

1278 kmDistance

116kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$158 - $513	Average Duration1d 3h	CO₂ emissions 32kg CO₂e
Train	Average Price$272 - $1,584	Average Duration22h 2m	CO₂ emissions 116kg CO₂e

Train companies

Amtrak

4/55,574 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5574 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $272

US train and bus companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Where are the popular train stations and stops in Syracuse, US and St. Louis?

Stops in Syracuse, US

A - Regional Transportation Center

B - Syracuse Airport

Stops in St. Louis

A - Gateway Station

Frequently asked questions on the trip Syracuse, US - St. Louis

How much does a cheap train ticket from Syracuse to St. Louis cost?
The average train ticket price from Syracuse to St. Louis is $379. The best way to find cheap train tickets from Syracuse to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Syracuse to St. Louis?
A train trip between Syracuse and St. Louis is around 22h 2m, although the fastest train will take about 22h 2m. This is the time it takes to travel the 1280 km that separates the two cities.
How many daily trains are there between Syracuse and St. Louis?
The number of trains from Syracuse to St. Louis can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Syracuse to St. Louis by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Syracuse to St. Louis?
When taking the train from Syracuse to St. Louis, you can travel comfortably and safely with Amtrak.
What are the departure and arrival stations for a train from Syracuse to St. Louis?
Trains travelling between Syracuse and St. Louis leave from Regional Transportation Center or Syracuse Airport and arrive at Gateway Station.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-08

$416

11-09

$353

Today

$261

11-11

$301

11-12

$291

11-13

No data

11-14

$238

11-15

$212

The cheapest trip from Syracuse, US to St. Louis was searched and found on Nov 15, 2025 with a price of $212

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to St. Louis, as early as possible.

You can expect to pay from $212 to $1,624 for a train ticket from Syracuse, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $212 which is on 2025-11-15.