Train from Jacksonville, FL to Florence, SC, US: Tickets & Schedules

Next train departures

Next departures for Jacksonville to Florence on November 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Jacksonville Amtrak Station
Florence StationCheapest
AmtrakTrain
Jacksonville Amtrak Station
Florence StationFastest
AmtrakTrain
Jacksonville Amtrak Station
Florence StationNo tags
AmtrakTrain
Jacksonville Amtrak Station
Florence StationNo tags
AmtrakTrain
Jacksonville Amtrak Station
Florence StationNo tags

Last refresh of the prices: Yesterday at 8:20 AM EST.

Compare 2 ways to go from Jacksonville to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 5 hours 35 minutes, and with fares starting at just $75, it presents an excellent value for a comfortable ride.

2bus per day
5h 35mAverage Duration
465 kmDistance
12kgCO₂ emissions
Average Price$75 - $137Average Duration5h 35m
12kg CO₂e
Average Price$91 - $207Average Duration6h 11m
42kg CO₂e

Frequently asked questions about travelling from Jacksonville, FL to Florence, SC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Jacksonville to Florence?

    The cheapest train tickets from Jacksonville to Florence start at $91. The average price for this train route is around $136. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

  2. How long is the train ride from Jacksonville to Florence?

    The average train trip from Jacksonville to Florence takes 6h 11m and covers 465 km. The quickest train gets you there in 6h 11m and is operated by Amtrak.

  3. Which train operators serve the Jacksonville to Florence route?

    Several major train operators serve this route, with 2 trains available per day.

  4. What are the earliest and latest departure times for the train from Jacksonville to Florence?

    The earliest train from Jacksonville to Florence departs at 5:11pm. The latest train departs at 10:33pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-27
$107
11-28
$160
Today
$213
11-30
No data
12-01
No data
12-02
No data
12-03
No data
12-04
No data
busbud logoThe cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on Nov 27, 2025 with a price of $107

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville, FL to Florence, SC, US, as early as possible.

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