Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Louisville, KY | CheapestFastest |
Last refresh of the prices: Last Saturday at 8:20 PM EST.
Get from Syracuse to Louisville
The journey takes about 1 day, 1 hour, and with fares starting at just $282, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Louisville?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Louisville
- A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Compare bus companies
Frequently asked questions about travelling from Syracuse, US to Louisville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Louisville?
The cheapest bus tickets from Syracuse to Louisville start from $282. The average price for this route is around $291. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Louisville?
The average bus travel time from Syracuse to Louisville is 1d 1h, covering a distance of 971 km. The quickest bus can get you there in 22h 25m and is operated by Greyhound.
Which bus companies service the Syracuse to Louisville route?
What are the earliest and latest departure times for the bus from Syracuse to Louisville?
The earliest bus departs from Syracuse to Louisville at 4:30am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Louisville?
A bus trip from Syracuse to Louisville generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to Louisville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.
Which bus company has the best Wi-Fi from Syracuse to Louisville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Syracuse to Louisville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Louisville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Louisville was searched and found on Feb 2, 2026 with a price of $213To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Louisville, as early as possible.
