Bus from Santa Fe, AR to San Francisco, AR: Tickets & Schedules

Next bus departures

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Next departures for Santa Fe to San Francisco on February 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
La 20 de JunioBus
Estación Terminal de Ómnibius, Santa Fe
Terminal San FranciscoCheapest
ZenitBus
Estación Terminal de Ómnibius, Santa Fe
Terminal San FranciscoFastest
ZenitBus
Estación Terminal de Ómnibius, Santa Fe
Terminal San FranciscoNo tags
El PracticoBus
Estación Terminal de Ómnibus
Terminal San FranciscoNo tags
Crucero del SurBus
Estación Terminal de Ómnibius, Santa Fe
Terminal San FranciscoNo tags

Last refresh of the prices: Yesterday at 5:07 PM -03.

View all departures

Get from Santa Fe to San Francisco

This route is served by bus only

The journey takes about 2 hours 5 minutes, and with fares starting at just $16, it presents an excellent value for a comfortable ride.

15bus per day
2h 5mAverage Duration
134 kmDistance
3kgCO₂ emissions

Frequently asked questions about travelling from Santa Fe, AR to San Francisco, AR by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Santa Fe to San Francisco?

    The cheapest bus tickets from Santa Fe to San Francisco start from $16. The average price for this route is around $21. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Santa Fe to San Francisco?

    The average bus travel time from Santa Fe to San Francisco is 2h 5m, covering a distance of 134 km. The quickest bus can get you there in 1h 30m and is operated by Zenit.

  3. Which bus companies service the Santa Fe to San Francisco route?

    Several major bus companies operate on this route with 15 buses available per day, including services from Zenit, El Practico, 20 de Junio, Andesmar, Dumascat, Flechabus, Rio Uruguay, Transporte Serrano, Crucero del Sur - Tmo. Parque, Río Uruguay.

  4. What are the earliest and latest departure times for the bus from Santa Fe to San Francisco?

    The earliest bus departs from Santa Fe to San Francisco at 12:30am. And the latest bus departs at 10:15pm.

  5. What are the CO₂ emissions for the bus trip from Santa Fe to San Francisco?

    A bus trip from Santa Fe to San Francisco generates an estimated 3 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Santa Fe to San Francisco?

    According to Busbud customers, the highest-rated bus company on this route is Dumascat, with an average rating of 4.7 out of 5 stars based on 64 reviews.

  7. Which bus company has the best Wi-Fi from Santa Fe to San Francisco?

    Based on Busbud reviews, the bus company Río Uruguay has the highest Wi-Fi rating with a score of 5.0.

  8. Which bus company has the best on-time performance from Santa Fe to San Francisco?

    According to Busbud traveller reviews, the most punctual bus company on this route is Río Uruguay, with a punctuality rating of 5.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Santa Fe to San Francisco?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Dumascat, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02-19
$15
02-20
$16
Today
$16
02-22
$15
02-23
$15
02-24
$15
02-25
$15
02-26
$15
busbud logoThe cheapest trip from Santa Fe, AR to San Francisco, AR was searched and found on Feb 19, 2026 with a price of $15

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to San Francisco, AR, as early as possible.

You can expect to pay from $15 to $37 for a bus ticket from Santa Fe, AR to San Francisco, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $15 which is on 2026-02-23.

Usually Crucero del Sur - Tmo. Parque will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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