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- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
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Bus Santa Cruz de la Sierra, BO to Uyuni: Trip Overview
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Santa Cruz de la Sierra to Uyuni Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Cruz de la Sierra to Uyuni.
We make it our job to connect you with the most dependable bus companies that cover bus service from Santa Cruz de la Sierra to Uyuni.
Discover how much the bus trip from Santa Cruz de la Sierra to Uyuni will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Santa Cruz de la Sierra and Uyuni?
Frequently asked questions on the trip Santa Cruz de la Sierra, BO - Uyuni
What is the travel distance from Santa Cruz de la Sierra to Uyuni?
The distance between Santa Cruz de la Sierra and Uyuni is around 486 km (302 miles).
What are the departure and arrival locations for buses traveling from Santa Cruz de la Sierra to Uyuni?
Buses traveling this route start their trip at Estacion Bimodal, in Santa Cruz de la Sierra, and end it at Terminal de Autobuses de Uyuni, in Uyuni.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Cruz de la Sierra, BO to Uyuni was searched and found on Aug 10, 2025 with a price of US$41To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Cruz de la Sierra, BO to Uyuni, as early as possible.
You can expect to pay from US$41 to US$41 for a bus ticket from Santa Cruz de la Sierra, BO to Uyuni based on the last 2 days. You can expect to find the cheapest price for the trip at US$41 which is on 2025-08-13.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Cruz de la Sierra to Uyuni but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santa Cruz de la Sierra to Uyuni.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santa Cruz de la Sierra to Uyuni will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Cruz de la Sierra to Uyuni.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
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Popular Buses Connecting Santa Cruz de la Sierra
Buses Leaving from Santa Cruz de la Sierra
- Bus from Santa Cruz de la Sierra to Uyuni
- Bus Santa Cruz de la Sierra - Buenos Aires
- Santa Cruz de la Sierra - Asunción
- Bus from Santa Cruz de la Sierra to Puerto Quijarro
- Bus Santa Cruz de la Sierra - Cochabamba
- Santa Cruz de la Sierra - Trinidad
- Bus from Santa Cruz de la Sierra to Oruro
- Bus Santa Cruz de la Sierra - San Ignacio de Velasco
- Santa Cruz de la Sierra - Roboré
- Bus from Santa Cruz de la Sierra to São Paulo
- Bus Santa Cruz de la Sierra - Liniers
- Santa Cruz de la Sierra - Campana
- Bus from Santa Cruz de la Sierra to El Talar de Pacheco
Buses Going to Santa Cruz de la Sierra
- Bus from Buenos Aires to Santa Cruz de la Sierra
- Bus Cochabamba - Santa Cruz de la Sierra
- São Paulo - Santa Cruz de la Sierra
- Bus from Tarija to Santa Cruz de la Sierra
- Bus La Paz - Santa Cruz de la Sierra
- Asunción - Santa Cruz de la Sierra
- Bus from Yacuíba to Santa Cruz de la Sierra
- Bus Trinidad - Santa Cruz de la Sierra
- Puerto Quijarro - Santa Cruz de la Sierra
- Bus from San Ignacio de Velasco to Santa Cruz de la Sierra
- Bus Oruro - Santa Cruz de la Sierra
- Villazon - Santa Cruz de la Sierra
- Bus from Roboré to Santa Cruz de la Sierra
- Bus Liniers - Santa Cruz de la Sierra
- El Talar de Pacheco - Santa Cruz de la Sierra
Popular Buses Connecting Uyuni
Buses Leaving from Uyuni
Buses Going to Uyuni
Popular routes in this country
- Bus from La Paz to Rurrenabaque
- Bus La Paz - Sucre
- Santa Cruz de la Sierra - Sucre
- Bus from Uyuni to Sucre
- Bus Sucre - Potosi
- Cochabamba - La Paz
- Bus from Potosi to Uyuni
- Bus Santa Cruz de la Sierra - La Paz
- Potosi - Sucre
- Bus from Santa Cruz de la Sierra to Yacuíba
- Bus La Paz - Oruro
- Sucre - Samaipata
- Bus from Oruro to Uyuni
- Bus Uyuni - Villazon
- Oruro - La Paz