Bus Tickets from Rome to Lyon

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TodayAug 8
from US$101
TomorrowAug 9
from US$93
SunAug 10
from US$100
MonAug 11
from US$86
TueAug 12
from US$86
WedAug 13
from US$93
ThuAug 14
from US$93
FriAug 15

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 9 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: August 9 at
    Destination city: Lyon
    Destination location: Lyon Lyon Perrache Bus Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: August 10 at
    Destination city: Lyon
    Destination location: Lyon - Perrache Bus Station
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: August 9 at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: August 9 at
    Destination city: Lyon
    Destination location: Lyon Lyon Perrache Bus Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: August 10 at
    Destination city: Lyon
    Destination location: Aéroport LYS
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 11:41 AM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Rome to Lyon

Bus
Average PriceUS$52 - US$257Average Duration16h 55m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$179 - US$407Average Duration8h 12m
18kg CO₂e5 out of 5 stars
Fastest
Carpool
Average PriceUS$66 - US$97Average Duration10h 40m
31kg CO₂e4 out of 5 stars
busbud logoBusbud recommends carpooling from Rome to Lyon

Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 10 hours 40 minutes, and with fares starting at just US$66, it presents an excellent value for a comfortable ride.

2carpool per day
10h 40mAverage Duration
US$66Cheapest ticket
31kgCO₂ emissions

Bus Rome to Lyon: Trip Overview

Average Ticket PriceUS$102
Average Bus Trip Duration16h 55m
Number of daily buses19
Earliest bus departure12:10am
Distance732 km
Latest bus departure11:50pm

Rome to Lyon Bus

Busbud helps you find a bus from Rome to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Rome to Lyon from the most reliable bus companies operating this trip.

Discover how much the bus trip from Rome to Lyon will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Rome - Lyon

  1. What is the distance between Rome and Lyon?

    The distance between Rome and Lyon is approximately 748 km (464 miles).

  2. What are the departure and arrival locations for buses traveling from Rome to Lyon?

    Buses departing from Rome Ciampino Airport in Rome will take you to Lyon Airport in Lyon.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-06
US$83
08-07
US$76
Today
US$96
08-09
US$84
08-10
US$91
08-11
US$78
08-12
US$78
08-13
US$84
busbud logoThe cheapest trip from Rome to Lyon was searched and found on Aug 7, 2025 with a price of US$76

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon, as early as possible.

You can expect to pay from US$76 to US$227 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at US$78 which is on 2025-08-12.

Usually Flixbus (IT), Comuto Pro (BlaBlaCar Bus) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rome and Lyon!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Lyon, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rome to Lyon will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Lyon.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Rome by bus?

Bus from Rome to Lyon

You can also go to Lyon by train

Train from Rome to Lyon

Why choose Busbud?

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