Bus Tickets from Rome to Karlsruhe

Next departures

Next departures for Rome to Karlsruhe on September 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
MarinoBus
Rome Tiburtina Bus Station
Südseite HauptbahnhofCheapestFastest

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Rome to Karlsruhe: Trip Overview

Average Ticket PriceUS$147
Average Bus Trip Duration18h 45m
Number of daily buses3
Earliest bus departure5:15am
Distance850 km
Latest bus departure11:50pm

Rome to Karlsruhe Bus

With Busbud, comparing and booking tickets for a bus from Rome to Karlsruhe is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Rome to Karlsruhe from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Rome to Karlsruhe, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Rome - Karlsruhe

  1. What is the travel distance from Rome to Karlsruhe?

    The distance between Rome and Karlsruhe is approximately 854 km (530 miles).

  2. What are the departure and arrival locations for buses traveling from Rome to Karlsruhe?

    Buses departing from Rome Tiburtina Bus Station in Rome will take you to Südseite Hauptbahnhof in Karlsruhe.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-01
No data
09-02
US$133
Today
No data
09-04
US$142
09-05
No data
09-06
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09-07
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09-08
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busbud logoThe cheapest trip from Rome to Karlsruhe was searched and found on Sep 2, 2025 with a price of US$133

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Karlsruhe, as early as possible.

You can expect to pay from US$133 to US$142 for a bus ticket from Rome to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at US$142 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Rome to Karlsruhe.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Karlsruhe, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rome to Karlsruhe that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Karlsruhe.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Rome by bus?

Bus from Karlsruhe to Rome

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