Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Aeroporto Ciampino Airport (CIA) | Caltanissetta (Via Rochester) | Cheapest | ||||
| Bus | Rome Tiburtina Bus Station | Caltanissetta (Via Rochester) | Fastest | ||||
| Bus | Rome Tiburtina Bus Station | Caltanissetta (Via Rochester) | No tags | ||||
| Bus | Rome Anagnina | Caltanissetta (Via Rochester) | No tags | ||||
| Bus | Aeroporto Ciampino Airport (CIA) | Caltanissetta (Via Rochester) | No tags |
Last refresh of the prices: Last Wednesday at 3:20 PM CET.
Get from Rome to Caltanissetta
The journey takes about 16 hours, and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Where are the popular stops in Rome and Caltanissetta?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Caltanissetta
- A
Corso Vittorio Emanuele II
Corso Vittorio Emanuele II, 97, 93100 Caltanissetta CL, Italy
Compare bus companies
Based on 12375 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at $56
Frequently asked questions about travelling from Rome to Caltanissetta by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Caltanissetta?
The cheapest bus tickets from Rome to Caltanissetta start from $56. The average price for this route is around $141. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Caltanissetta?
The average bus travel time from Rome to Caltanissetta is 16h, covering a distance of 509 km. The quickest bus can get you there in 13h 15m and is operated by FlixBus.
Which bus companies service the Rome to Caltanissetta route?
Several major bus companies operate on this route with 5 buses available per day.
What are the earliest and latest departure times for the bus from Rome to Caltanissetta?
The earliest bus departs from Rome to Caltanissetta at 4:05am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Rome to Caltanissetta?
A bus trip from Rome to Caltanissetta generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Caltanissetta was searched and found on Mar 31, 2026 with a price of $63To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Caltanissetta, as early as possible.
You can expect to pay from $63 to $185 for a bus ticket from Rome to Caltanissetta based on the last 2 days. You can expect to find the cheapest price for the trip at $63 which is on 2026-03-31.
