Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Roanoke Bus Stop | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Roanoke Bus Stop | Downtown Transit Center | No tags | ||||
| Bus | Roanoke Bus Stop | Indianapolis Bus Station | No tags | ||||
| Bus | Roanoke Bus Stop | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Roanoke Bus Stop | Downtown Transit Center | No tags |
Compare 2 ways to go from Roanoke to Indianapolis
Among the sustainable travel choices, the Train stands out as a good way to reach Indianapolis. The journey takes about 21 hours 17 minutes, and with fares starting at just $125, it presents an excellent value for a comfortable ride.
Where are the popular stops in Roanoke and Indianapolis?
Stops in Roanoke
- AExit 140 (Park and Ride), Virginia 24153, USA
Compare bus companies
Based on 87523 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $129
Greyhound Roanoke Indianapolis recent customer reviews
It was way too cramped...totally sore after this trip
Danny C.
Frequently asked questions about travelling from Roanoke to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Roanoke to Indianapolis?
The cheapest bus tickets from Roanoke to Indianapolis start from $129. The average price for this route is around $156. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Roanoke to Indianapolis?
The average bus travel time from Roanoke to Indianapolis is 19h 35m, covering a distance of 608 km. The quickest bus can get you there in 15h 55m and is operated by Greyhound.
Which bus companies service the Roanoke to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Roanoke to Indianapolis?
The earliest bus departs from Roanoke to Indianapolis at 4:35am. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from Roanoke to Indianapolis?
A bus trip from Roanoke to Indianapolis generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Roanoke to Indianapolis was searched and found on Feb 15, 2026 with a price of $136To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Indianapolis, as early as possible.
You can expect to pay from $136 to $264 for a bus ticket from Roanoke to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $140 which is on 2026-02-20.
