Bus Tickets from Portland, OR to San Diego, CA, US
Next bus departures
Next departures for Portland to San Diego on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
CheapestFastest
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
Downtown SD (Seaport)
No tags
Next departures for Portland to San Diego on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Next departures for Portland to San Diego on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Next departures for Portland to San Diego on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
Fastest
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Next departures for Portland to San Diego on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
Fastest
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Next departures for Portland to San Diego on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
Fastest
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Next departures for Portland to San Diego on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
Downtown SD (Seaport)
No tags
Next departures for Portland to San Diego on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Portland Curbside Bus Stop
Greyhound Bus Stop
Fastest
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
San Diego (Old Town-FlixBus)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Portland Curbside Bus Stop
UCSD Health La Jolla Station
No tags
Last refresh of the prices: Last Thursday at 2:35 PM PST.
Compare 2 ways to go from Portland to San Diego
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 1 day, 10 hours 28 minutes, and with fares starting at just $231, it presents an excellent value for a comfortable ride.
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $323
Based on 11428 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $222
Frequently asked questions about travelling from Portland, OR to San Diego, CA, US by bus
What is the travel distance from Portland to San Diego?
The distance between Portland and San Diego is approximately 1503 km (932 miles).
What are the departure and arrival locations for buses traveling from Portland to San Diego?
Buses departing from Portland Union Station in Portland will take you to Mission Valley Sheraton in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-22
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11-23
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Today
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11-25
No data
11-26
$458
11-27
No data
11-28
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11-29
No data
The cheapest trip from Portland, OR to San Diego, CA, US was searched and found on Nov 26, 2025 with a price of $458
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to San Diego, CA, US, as early as possible.
You can expect to pay from $458 to $458 for a bus ticket from Portland, OR to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $458 which is on 2025-11-26.
What's the cheapest way to go from Portland, OR to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from Portland, OR to San Diego, CA, US was searched and found on Nov 26, 2025 with a price of $458
The bus is the cheapest travel choice for this destination
