Bus Tickets from Philadelphia, PA to Des Moines

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TodayJul 13
TomorrowJul 14
TueJul 15
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ThuJul 17
from US$166
FriJul 18
SatJul 19
SunJul 20

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: July 17 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: July 18 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 17 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: July 18 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 17 at
    Departure city: Philadelphia
    Departure location: Frazer - 56-40 Matthews Rd
    Arrival time: July 19 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 11:33 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Philadelphia to Des Moines: Trip Overview

Average Ticket PriceUS$177
Average Bus Trip Duration1d 12h
Number of daily buses2
Earliest bus departure3:25am
Distance1528 km
Latest bus departure10:55am

Philadelphia to Des Moines Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Philadelphia to Des Moines.

We make sure you can find a bus service from Philadelphia to Des Moines from the most reliable bus companies operating this trip.

Discover how much the bus trip from Philadelphia to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia, PA - Des Moines

  1. What is the distance between Philadelphia and Des Moines?

    The distance covered from Philadelphia to Des Moines is 1563 km (969 miles).

  2. What are the departure and arrival locations for buses traveling from Philadelphia to Des Moines?

    Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Jefferson/Trailways Depot, in Des Moines.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-11
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07-12
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Today
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07-14
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07-15
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07-16
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07-17
US$158
07-18
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busbud logoThe cheapest trip from Philadelphia to Des Moines was searched and found on Jul 17, 2025 with a price of US$158

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to Des Moines, as early as possible.

You can expect to pay from US$158 to US$158 for a bus ticket from Philadelphia to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$158 which is on 2025-07-17.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Philadelphia to Des Moines but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Philadelphia to Des Moines, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Philadelphia to Des Moines will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Philadelphia to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to Des Moines

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