Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 24 atDeparture city: OrlandoDeparture location: Orlando Bus StationArrival time: June 25 atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: June 24 atDeparture city: OrlandoDeparture location: Orlando Bus StationArrival time: June 25 atDestination city: St LouisDestination location: Gateway StationOperated by: FlixBus
Vehicle: BusDuration: - Departure time: June 24 atDeparture city: OrlandoDeparture location: Orlando Bus StationArrival time: June 25 atDestination city: St LouisDestination location: Gateway StationOperated by: FlixBusVehicle: BusDuration:
Last refresh of the prices: Last Tuesday at 1:53 AM EDT.
Prices and availability are subject to change.
Accepted payments
Compare 2 ways to go from Orlando to St Louis
Busbud recommends taking the bus from Orlando to St LouisAmong the sustainable travel choices, the bus stands out as a good way to reach St Louis. The journey takes about 21 hours 55 minutes, and with fares starting at just US$75, it presents an excellent value for a comfortable ride.
Bus Orlando to St Louis: Trip Overview
Compare bus companies
Orlando to St Louis Bus
Busbud helps you find a bus from Orlando to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to St Louis.
Whether it is cheap bus tickets or more luxurious buses going to St Louis from Orlando, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Orlando and St Louis?
Frequently asked questions on the trip Orlando - St Louis
How far is Orlando from St Louis?
It's about 1388 km (861 miles) from Orlando to St Louis.
What are the departure and arrival locations for buses traveling from Orlando to St Louis?
Buses departing from Orlando Bus Station in Orlando will take you to Gateway Station in St Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to St Louis was searched and found on Jun 28, 2025 with a price of US$74To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to St Louis, as early as possible.
You can expect to pay from US$74 to US$180 for a bus ticket from Orlando to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$74 which is on 2025-06-28.
Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Orlando and St Louis!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Orlando to St Louis.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to St Louis.
Tune out to the fine sounds of your best music playlist on your bus trip from Orlando to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
What's the cheapest way to go from Orlando to St Louis?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Orlando
Buses Leaving from Orlando
- Bus from Orlando to Melbourne
- Bus Orlando - Tampa
- Orlando - Jacksonville
- Bus from Orlando to Jacksonville
- Bus Orlando - Atlanta
- Orlando - Fort Lauderdale
- Bus from Orlando to Gainesville
- Bus Orlando - St. Petersburg
- Orlando - Daytona Beach
- Bus from Orlando to Kissimmee
- Bus Orlando - Bradenton
- Orlando - West Palm Beach
- Bus from Orlando to Pompano Beach
Buses Going to Orlando
- Bus from Tampa to Orlando
- Bus Atlanta - Orlando
- Fort Lauderdale - Orlando
- Bus from Chicago to Orlando
- Bus Orange - Orlando
- Ocala - Orlando
- Bus from Bradenton to Orlando
- Bus Hollywood - Orlando
- Pompano Beach - Orlando
- Bus from Gainesville to Orlando
- Bus New York - Orlando
- St. Petersburg - Orlando
- Bus from Buffalo to Orlando