Bus Tickets from Orlando to Key Largo

Next departures

Next departures for Orlando to Key Largo on October 14
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Orlando Bus Station
Key LargoCheapestFastest

Last refresh of the prices: Yesterday at 12:24 AM EDT.

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Bus Orlando to Key Largo: Trip Overview

Average Ticket PriceUS$40
Average Bus Trip Duration7h 55m
Number of daily buses3
Earliest bus departure1:15am
Distance385 km
Latest bus departure10:35pm

Orlando to Key Largo Bus

Busbud helps you find a bus from Orlando to Key Largo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Orlando to Key Largo will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Orlando to Key Largo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Orlando - Key Largo

  1. What is the distance between Orlando and Key Largo?

    It's about 396 km (246 miles) from Orlando to Key Largo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-12
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Today
US$44
10-15
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busbud logoThe cheapest trip from Orlando to Key Largo was searched and found on Oct 14, 2025 with a price of US$44

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Key Largo, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Orlando and Key Largo!

Much more than a mere vehicle taking you from Orlando to Key Largo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Orlando to Key Largo that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Orlando to Key Largo while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Orlando by bus?

Bus from Key Largo to Orlando

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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