Bus from Orlando to Indianapolis: Tickets & Schedules

Next bus departures

Next departures for Orlando to Indianapolis on December 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus StationCheapest
Greyhound Lines, Inc.Bus
Orlando Bus Station
Indianapolis Bus StationFastest
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus StationNo tags
FlixBusBus
Orlando Bus Station
Downtown Transit CenterNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus StationNo tags

Last refresh of the prices: Last Sunday at 10:43 PM EST.

Compare 2 ways to go from Orlando to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 22 hours 5 minutes, and with fares starting at just $148, it presents an excellent value for a comfortable ride.

10bus per day
22h 5mAverage Duration
1321 kmDistance
33kgCO₂ emissions
Average Price$148 - $465Average Duration22h 5m
33kg CO₂e
Average Price$336 - $710Average Duration1d 15h
120kg CO₂e

Frequently asked questions about travelling from Orlando to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Orlando to Indianapolis?

    The cheapest bus tickets from Orlando to Indianapolis start from $148. The average price for this route is around $206. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Orlando to Indianapolis?

    The average bus travel time from Orlando to Indianapolis is 22h 5m, covering a distance of 1321 km. The quickest bus can get you there in 19h 55m and is operated by Greyhound.

  3. Which bus companies service the Orlando to Indianapolis route?

    Several major bus companies operate on this route with 10 buses available per day, including services from FlixBus, Greyhound.

  4. What are the earliest and latest departure times for the bus from Orlando to Indianapolis?

    The earliest bus departs from Orlando to Indianapolis at 5:15am. And the latest bus departs at 10:55pm.

  5. What are the CO₂ emissions for the bus trip from Orlando to Indianapolis?

    A bus trip from Orlando to Indianapolis generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Orlando to Indianapolis?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Orlando to Indianapolis?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Orlando to Indianapolis?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Orlando to Indianapolis?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-30
$281
12-01
$317
Today
$228
12-03
$170
12-04
$177
12-05
$164
12-06
$175
12-07
$198
busbud logoThe cheapest trip from Orlando to Indianapolis was searched and found on Dec 5, 2025 with a price of $164

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Indianapolis, as early as possible.

You can expect to pay from $164 to $349 for a bus ticket from Orlando to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $164 which is on 2025-12-05.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Orlando to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

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