How much is the bus ticket from Milwaukee to San Diego?

The cheapest bus tickets from Milwaukee to San Diego start from $182. The average price for this route is around $260. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Milwaukee to San Diego?

The average bus travel time from Milwaukee to San Diego is 2d 15h, covering a distance of 2788 km. The quickest bus can get you there in 2d 10h and is operated by FlixBus .

Which bus companies service the Milwaukee to San Diego route?

Several major bus companies operate on this route with 25 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from Milwaukee to San Diego?

The earliest bus departs from Milwaukee to San Diego at 6:30am. And the latest bus departs at 8:05pm.

What are the CO₂ emissions for the bus trip from Milwaukee to San Diego?

A bus trip from Milwaukee to San Diego generates an estimated 70 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Milwaukee to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87522 reviews.

Which bus company has the best Wi-Fi from Milwaukee to San Diego?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Milwaukee to San Diego?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Milwaukee to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Milwaukee to San Diego from $176 | Refundable Tickets

Next bus departures

Next departures for Milwaukee to San Diego on February 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 16h	10:05am	Downtown SD (Seaport)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:20am	Milwaukee Mitchell MKE Airport	2d 6h	1:40pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:00am	Milwaukee Bus Station, St. Paul & N6th road.	2d 7h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 17h	11:45am	Greyhound Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	12:50pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 7h	6:10pm	San Diego (Old Town-FlixBus)	No tags

Next departures for Milwaukee to San Diego on February 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Goerke's Corners Park & Ride (Brookfield)	2d 18h	11:45am	Greyhound Bus Stop	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	1:10pm	Milwaukee Mitchell MKE Airport	2d 6h	5:35pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:00am	Milwaukee Bus Station, St. Paul & N6th road.	2d 9h	4:25pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 17h	11:45am	Greyhound Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	12:50pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 7h	6:10pm	San Diego (Old Town-FlixBus)	No tags

Next departures for Milwaukee to San Diego on February 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	12:50pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 13h	11:50pm	Greyhound Bus Stop	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	1:10pm	Milwaukee Mitchell MKE Airport	2d 6h	5:35pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:00am	Milwaukee Bus Station, St. Paul & N6th road.	2d 9h	4:25pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 17h	11:45am	Greyhound Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	12:50pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 7h	6:10pm	San Diego (Old Town-FlixBus)	No tags

Next departures for Milwaukee to San Diego on February 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	9:00am	Milwaukee Bus Station, St. Paul & N6th road.	2d 7h	2:10pm	San Diego (Old Town-FlixBus)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:20am	Milwaukee Mitchell MKE Airport	2d 6h	1:40pm	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 20h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 17h	11:45am	Greyhound Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:00am	Milwaukee Bus Station, St. Paul & N6th road.	2d 6h	1:40pm	UCSD Health La Jolla Station	No tags

Next departures for Milwaukee to San Diego on February 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	2d 17h	10:15pm	Downtown SD (Seaport)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	2d 9h	1:40pm	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	2d 9h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	2d 13h	5:45pm	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:55pm	Milwaukee Bus Station, St. Paul & N6th road.	2d 20h	2:10pm	San Diego (Old Town-FlixBus)	No tags

Last refresh of the prices: Last Wednesday at 3:27 PM CST.

Compare 2 ways to go from Milwaukee to San Diego

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach San Diego. The journey takes about 2 days, 3 hours 53 minutes, and with fares starting at just $450, it presents an excellent value for a comfortable ride.

4train per day

2d 3hAverage Duration

2794 kmDistance

254kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$182 - $734	Average Duration2d 15h	CO₂ emissions 70kg CO₂e
Train	Average Price$450 - $454	Average Duration2d 3h	CO₂ emissions 254kg CO₂e

Where are the popular stops in Milwaukee and San Diego?

Stops in Milwaukee

A
Milwaukee Airport
Visit page
B
Intermodal Station
433 W St Paul Ave, Milwaukee, WI 53203, USA
Visit page
C
S Cesar Chavez
1016 S Cesar E Chavez Dr, Milwaukee, WI 53204, USA

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,522 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wi‑Fi2.5

FlixBus

3.5/512,210 reviews

Staff4.2

Timeliness4

Cleanliness4.1

Wi‑Fi2.7

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Milwaukee to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Milwaukee to San Diego?
The cheapest bus tickets from Milwaukee to San Diego start from $182. The average price for this route is around $260. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milwaukee to San Diego?
The average bus travel time from Milwaukee to San Diego is 2d 15h, covering a distance of 2788 km. The quickest bus can get you there in 2d 10h and is operated by FlixBus.
Which bus companies service the Milwaukee to San Diego route?
Several major bus companies operate on this route with 25 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Milwaukee to San Diego?
The earliest bus departs from Milwaukee to San Diego at 6:30am. And the latest bus departs at 8:05pm.
What are the CO₂ emissions for the bus trip from Milwaukee to San Diego?
A bus trip from Milwaukee to San Diego generates an estimated 70 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milwaukee to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87522 reviews.
Which bus company has the best Wi-Fi from Milwaukee to San Diego?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Milwaukee to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Milwaukee to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

02-11

$348

02-12

$213

Today

$484

02-14

$321

02-15

$220

02-16

$197

02-17

$287

02-18

$312

The cheapest trip from Milwaukee to San Diego, CA, US was searched and found on Feb 16, 2026 with a price of $197

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to San Diego, CA, US, as early as possible.

You can expect to pay from $197 to $484 for a bus ticket from Milwaukee to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $197 which is on 2026-02-16.