Next departures for Milwaukee to San Diego on February 14
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Downtown SD (Seaport)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Mitchell MKE Airport
UCSD Health La Jolla Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Greyhound Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Next departures for Milwaukee to San Diego on February 15
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Goerke's Corners Park & Ride (Brookfield)
Greyhound Bus Stop
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Mitchell MKE Airport
UCSD Health La Jolla Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Greyhound Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Next departures for Milwaukee to San Diego on February 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Greyhound Bus Stop
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Mitchell MKE Airport
UCSD Health La Jolla Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Greyhound Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Next departures for Milwaukee to San Diego on February 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Mitchell MKE Airport
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Greyhound Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Milwaukee Bus Station, St. Paul & N6th road.
UCSD Health La Jolla Station
No tags
Next departures for Milwaukee to San Diego on February 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Downtown SD (Seaport)
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Milwaukee Bus Station, St. Paul & N6th road.
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Milwaukee Bus Station, St. Paul & N6th road.
San Diego (Old Town-FlixBus)
No tags
Last refresh of the prices: Last Wednesday at 3:27 PM CST.
Compare 2 ways to go from Milwaukee to San Diego
We recommend taking the train
Among the sustainable travel choices, the Train stands out as a good way to reach San Diego. The journey takes about 2 days, 3 hours 53 minutes, and with fares starting at just $450, it presents an excellent value for a comfortable ride.
Based on 87522 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $186
Based on 12210 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at $170
Frequently asked questions about travelling from Milwaukee to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milwaukee to San Diego?
The cheapest bus tickets from Milwaukee to San Diego start from $182. The average price for this route is around $260. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milwaukee to San Diego?
The average bus travel time from Milwaukee to San Diego is 2d 15h, covering a distance of 2788 km. The quickest bus can get you there in 2d 10h and is operated by FlixBus.
Which bus companies service the Milwaukee to San Diego route?
Several major bus companies operate on this route with 25 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Milwaukee to San Diego?
The earliest bus departs from Milwaukee to San Diego at 6:30am. And the latest bus departs at 8:05pm.
What are the CO₂ emissions for the bus trip from Milwaukee to San Diego?
A bus trip from Milwaukee to San Diego generates an estimated 70 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milwaukee to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87522 reviews.
Which bus company has the best Wi-Fi from Milwaukee to San Diego?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Milwaukee to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Milwaukee to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
02-11
$348
02-12
$213
Today
$484
02-14
$321
02-15
$220
02-16
$197
02-17
$287
02-18
$312
The cheapest trip from Milwaukee to San Diego, CA, US was searched and found on Feb 16, 2026 with a price of $197
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to San Diego, CA, US, as early as possible.
You can expect to pay from $197 to $484 for a bus ticket from Milwaukee to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $197 which is on 2026-02-16.
What's the cheapest way to go from Milwaukee to San Diego, CA, US?
The Bus is the cheapest travel choice for this destination