Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lampugnano bus station | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus | Lampugnano bus station | Prague (Main Railway Station) | Fastest | ||||
| Bus | Aeroporto Linate Airport (LIN) | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Aeroporto Linate Airport (LIN) | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Aeroporto Linate Airport (LIN) | Prague (Main Railway Station) | No tags |
Last refresh of the prices: Today at 1:59 AM CET.
Compare 2 ways to go from Milano to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 10 hours 10 minutes, and with fares starting at just $116, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$67 - $378 | Average Duration18h 10m | 17kg CO₂e | ||
Carpool | Average Price$116 - $116 | Average Duration10h 10m | 27kg CO₂e |
Where are the popular stops in Milano and Prague?
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- CPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - BAviatická, 161 08, Praha 6, Czechia
- CChlumecká, 198 00 Praha 20, Czech Republic
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about travelling from Milano to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milano to Prague?
The cheapest bus tickets from Milano to Prague start from $67. The average price for this route is around $126. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Prague?
The average bus travel time from Milano to Prague is 18h 10m, covering a distance of 661 km. The quickest bus can get you there in 13h and is operated by FlixBus.
Which bus companies service the Milano to Prague route?
Several major bus companies operate on this route with 72 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet, ALSA.
What are the earliest and latest departure times for the bus from Milano to Prague?
The earliest bus departs from Milano to Prague at 1:00am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Milano to Prague?
A bus trip from Milano to Prague generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milano to Prague?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61073 reviews.
Which bus company has the best Wi-Fi from Milano to Prague?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Milano to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Milano to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Prague was searched and found on Jan 12, 2026 with a price of $70To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Prague, as early as possible.
You can expect to pay from $70 to $234 for a bus ticket from Milano to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $70 which is on 2026-01-12.
