Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Key Largo | Downtown Transit Center | CheapestFastest | ||||
 | Bus | Key Largo | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Key Largo | Downtown Transit Center | No tags |
Last refresh of the prices: Last Saturday at 7:02 PM EST.
Get from Key Largo to Indianapolis
The journey takes about 1 day, 9 hours 5 minutes, and with fares starting at just $193, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87516 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $193
Frequently asked questions about travelling from Key Largo to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Key Largo to Indianapolis?
The cheapest bus tickets from Key Largo to Indianapolis start from $193. The average price for this route is around $210. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Key Largo to Indianapolis?
The average bus travel time from Key Largo to Indianapolis is 1d 9h, covering a distance of 1717 km. The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Key Largo to Indianapolis route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Key Largo to Indianapolis?
The earliest bus departs from Key Largo to Indianapolis at 12:40pm. And the latest bus departs at 7:40pm.
What are the CO₂ emissions for the bus trip from Key Largo to Indianapolis?
A bus trip from Key Largo to Indianapolis generates an estimated 43 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Key Largo to Indianapolis was searched and found on Jan 21, 2026 with a price of $185To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key Largo to Indianapolis, as early as possible.
You can expect to pay from $185 to $185 for a bus ticket from Key Largo to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $185 which is on 2026-01-25.
