Bus Tickets from Jacksonville, FL to Lafayette, IN

Find affordable bus tickets from Jacksonville, FL to Lafayette, IN with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 9
TomorrowAug 10
MonAug 11
TueAug 12
WedAug 13
from US$141
ThuAug 14
from US$122
FriAug 15
SatAug 16

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 13 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 14 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 13 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 14 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 13 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 14 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 13 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 14 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 13 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 15 at
    Destination city: Lafayette
    Destination location: Lafayette Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 3:31 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Jacksonville to Lafayette

Bus
Average PriceUS$122 - US$205Average Duration1d
30kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$411 - US$1,387Average Duration1d 14h
110kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Lafayette

Among the sustainable travel choices, the bus stands out as a good way to reach Lafayette. The journey takes about 1 day, 15 minutes, and with fares starting at just US$122, it presents an excellent value for a comfortable ride.

5bus per day
1d Average Duration
US$122Cheapest ticket
30kgCO₂ emissions

Bus Jacksonville, FL to Lafayette, IN: Trip Overview

Average Ticket PriceUS$154
Average Bus Trip Duration1d
Number of daily buses5
Earliest bus departure8:05am
Distance1217 km
Latest bus departure9:45pm

Jacksonville to Lafayette Bus

Busbud helps you find a bus from Jacksonville to Lafayette. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Jacksonville to Lafayette from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Lafayette from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Jacksonville, FL - Lafayette, IN

  1. How far is Jacksonville from Lafayette?

    The distance between Jacksonville and Lafayette is around 1216 km (754 miles).

  2. What are the departure and arrival locations for buses traveling from Jacksonville to Lafayette?

    Buses traveling this route start their trip at Jacksonville Amtrak Station, in Jacksonville, and end it at CityBus Center, in Lafayette.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-07
No data
08-08
No data
Today
No data
08-10
No data
08-11
No data
08-12
No data
08-13
US$154
08-14
No data
busbud logoThe cheapest trip from Jacksonville, FL to Lafayette, IN was searched and found on Aug 13, 2025 with a price of US$154

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Lafayette, IN, as early as possible.

You can expect to pay from US$154 to US$154 for a bus ticket from Jacksonville, FL to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at US$154 which is on 2025-08-13.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jacksonville and Lafayette!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Lafayette, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Jacksonville to Lafayette.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Jacksonville to Lafayette.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Jacksonville, FL to Lafayette, IN?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Jacksonville, FL to Lafayette, IN

You can also go to Lafayette, IN by train

Train from Jacksonville, FL to Lafayette, IN

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Jacksonville

Buses Leaving from Jacksonville

Buses Going to Jacksonville

Popular Buses Connecting Lafayette

Buses Leaving from Lafayette

Buses Going to Lafayette