Bus Tickets from Jacksonville, FL to Chicago

Next departures

Next departures for Jacksonville to Chicago on October 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Jacksonville Bus Station
Chicago 95Th & Dan RyanCheapest
FlixBus + Greyhound Lines, Inc.
Jacksonville Bus Station
Downtown Greyhound StationFastest
FlixBus + Greyhound Lines, Inc.
Jacksonville Bus Station
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
Jacksonville Bus Station
537-517 W. Jackson BlvdNo tags
Greyhound Lines, Inc. + FlixBus
Jacksonville Bus Station
Downtown Greyhound StationNo tags

Last refresh of the prices: Yesterday at 2:40 PM EDT.

Accepted payments

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Compare 2 ways to go from Jacksonville to Chicago

Bus
Average PriceUS$74 - US$320Average Duration1d 2h
35kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$128 - US$669Average Duration1d 16h
126kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Chicago

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 30 minutes, and with fares starting at just US$74, it presents an excellent value for a comfortable ride.

17bus per day
1d 2hAverage Duration
US$74Cheapest ticket
35kgCO₂ emissions

Bus Jacksonville, FL to Chicago: Trip Overview

Average Ticket PriceUS$124
Average Bus Trip Duration1d 2h
Number of daily buses17
Earliest bus departure9:05am
Distance1390 km
Latest bus departure9:45pm

Jacksonville to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Chicago.

We make it our job to connect you with the most dependable bus companies that cover bus service from Jacksonville to Chicago.

Discover how much the bus trip from Jacksonville to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Jacksonville, FL - Chicago

  1. How much does a bus ticket from Jacksonville to Chicago cost?

    The bus ticket price from Jacksonville to Chicago starts at US$74. The best way to find cheap bus tickets from Jacksonville to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Jacksonville to Chicago?

    The average travel time between Jacksonville and Chicago is around 1d 2h, although the fastest bus will take about 22h 45m.This is the time it takes to travel the 1390 km that separates the two cities.

  3. How many daily bus connections are there between Jacksonville and Chicago?

    The number of buses from Jacksonville to Chicago can differ depending on the day of the week. On average, there are 17 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Jacksonville to Chicago by comparing and selecting the bus that fits you travel style and budget on Busbud.

  4. Which bus companies travel from Jacksonville to Chicago?

    When taking the bus from Jacksonville to Chicago, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Jacksonville to Chicago?

    Buses travelling between Jacksonville and Chicago leave from Jacksonville Amtrak Station or W Forsyth St and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-28
US$134
09-29
US$111
Today
US$223
10-01
US$136
10-02
US$159
10-03
US$85
10-04
US$81
10-05
US$111
busbud logoThe cheapest trip from Jacksonville, FL to Chicago was searched and found on Oct 4, 2025 with a price of US$81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Chicago, as early as possible.

You can expect to pay from US$81 to US$223 for a bus ticket from Jacksonville, FL to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$81 which is on 2025-10-04.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Jacksonville to Chicago.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jacksonville to Chicago will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Jacksonville to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Jacksonville, FL to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Chicago to Jacksonville, FL

You can also go to Chicago by train

Train from Jacksonville, FL to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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