Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 1116 Woodruff Rd | Wilmington Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | 1116 Woodruff Rd | Wilmington Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | 1116 Woodruff Rd | Wilmington Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | 1116 Woodruff Rd | Wilmington Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | 1116 Woodruff Rd | Wilmington Bus Station | No tags |
Compare 2 ways to go from Greenville to Wilmington
Among the sustainable travel choices, the train stands out as a good way to reach Wilmington. The journey takes about 14 hours 19 minutes, and with fares starting at just $183, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Wilmington?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Wilmington
- AWilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
- B100 French St, Wilmington, DE 19801, USA
- C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801
Compare bus companies
Frequently asked questions about travelling from Greenville, SC to Wilmington, DE by bus
How far is Greenville from Wilmington?
Greenville and Wilmington are 813 km (504 miles) apart.
What are the departure and arrival locations for buses traveling from Greenville to Wilmington?
Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to Wilmington Bus Station in Wilmington.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Wilmington, DE was searched and found on Nov 26, 2025 with a price of $168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Wilmington, DE, as early as possible.
You can expect to pay from $168 to $428 for a bus ticket from Greenville, SC to Wilmington, DE based on the last 2 days. You can expect to find the cheapest price for the trip at $168 which is on 2025-11-26.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Greenville, SC to Wilmington, DE?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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