Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Cincinnati (University of Cincinnati) | Downtown SD (Seaport) | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Cincinnati (Downtown) | UCSD Health La Jolla Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Cincinnati Bus Station | San Diego (Old Town-FlixBus) | No tags | ||||
 | Bus | Cincinnati Bus Station | Greyhound Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Cincinnati Bus Station | UCSD Health La Jolla Station | No tags |
Last refresh of the prices: Last Saturday at 12:26 AM EDT.
Compare 2 ways to go from Cincinnati to San Diego
Among the sustainable travel choices, the Bus stands out as a good way to reach San Diego. The journey takes about 2 days, 11 hours 45 minutes, and with fares starting at just $241, it presents an excellent value for a comfortable ride.
Where are the popular stops in Cincinnati and San Diego?
Stops in Cincinnati
- A1005 Gilbert Ave, Cincinnati, OH 45202
- B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 87531 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $257
Frequently asked questions about travelling from Cincinnati to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Cincinnati to San Diego?
The cheapest bus tickets from Cincinnati to San Diego start from $241. The average price for this route is around $360. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Cincinnati to San Diego?
The average bus travel time from Cincinnati to San Diego is 2d 11h, covering a distance of 3014 km. The quickest bus can get you there in 2d 9h and is operated by Greyhound.
Which bus companies service the Cincinnati to San Diego route?
Several major bus companies operate on this route with 19 buses available per day.
What are the earliest and latest departure times for the bus from Cincinnati to San Diego?
The earliest bus departs from Cincinnati to San Diego at 12:55am. And the latest bus departs at 10:40am.
What are the CO₂ emissions for the bus trip from Cincinnati to San Diego?
A bus trip from Cincinnati to San Diego generates an estimated 75.34710000000001 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cincinnati to San Diego, CA, US was searched and found on Mar 29, 2026 with a price of $246To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to San Diego, CA, US, as early as possible.
You can expect to pay from $246 to $390 for a bus ticket from Cincinnati to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $332 which is on 2026-04-01.
What's the cheapest way to go from Cincinnati to San Diego, CA, US?
The Bus is the cheapest travel choice for this destination
