Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Gainesville Bus Stop | Cheapest | ||||
 | Bus | Chicago 95Th & Dan Ryan | Rosa Parks Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Gainesville Bus Stop | No tags | ||||
| Bus | Downtown Greyhound Station | Rosa Parks Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Gainesville Bus Stop | No tags |
Last refresh of the prices: Today at 5:31 PM CST.
Get from Chicago to Gainesville
The journey takes about 1 day, 3 hours 30 minutes, and with fares starting at just $134, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Gainesville?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Compare bus companies
Frequently asked questions about travelling from Chicago to Gainesville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Gainesville?
The cheapest bus tickets from Chicago to Gainesville start from $134. The average price for this route is around $230. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Gainesville?
The average bus travel time from Chicago to Gainesville is 1d 3h, covering a distance of 1434 km. The quickest bus can get you there in 21h 20m and is operated by FlixBus.
Which bus companies service the Chicago to Gainesville route?
Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus, Greyhound, Tornado Bus.
What are the earliest and latest departure times for the bus from Chicago to Gainesville?
The earliest bus departs from Chicago to Gainesville at 5:25am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Chicago to Gainesville?
A bus trip from Chicago to Gainesville generates an estimated 36 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Chicago to Gainesville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12162 reviews.
Which bus company has the best Wi-Fi from Chicago to Gainesville?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.9.
Which bus company has the best on-time performance from Chicago to Gainesville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Gainesville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Gainesville, FL was searched and found on Jan 30, 2026 with a price of $133To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Gainesville, FL, as early as possible.
You can expect to pay from $133 to $345 for a bus ticket from Chicago to Gainesville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $135 which is on 2026-02-01.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
