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- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 20 atDeparture city: CharlestonDeparture location: Charleston Bus StationArrival time: June 20 atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Last Sunday at 8:48 PM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Charleston to St Louis
Busbud recommends taking the bus from Charleston to St LouisAmong the sustainable travel choices, the bus stands out as a good way to reach St Louis. The journey takes about 15 hours 15 minutes, and with fares starting at just US$83, it presents an excellent value for a comfortable ride.
Bus Charleston to St Louis: Trip Overview
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Based on 87042 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$83.00
Charleston to St Louis Bus
With Busbud, comparing and booking tickets for a bus from Charleston to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Charleston to St Louis from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to St Louis from Charleston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Charleston and St Louis?
Frequently asked questions on the trip Charleston (WV), US - St Louis
How long is the trip from Charleston to St Louis by bus?
The typical travel time from Charleston to St Louis by bus is around 15h 15m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 15h 15m.
What is the travel distance from Charleston to St Louis?
The distance covered from Charleston to St Louis is 747 km (464 miles).
What are the departure and arrival locations for buses traveling from Charleston to St Louis?
Buses traveling this route start their trip at Charleston Greyhound Bus Station, in Charleston, and end it at Gateway Station, in St Louis.
What is the cheapest way to go from Charleston to St Louis?
If you're on a budget, consider traveling by bus to St Louis from Charleston; it tends to be more affordable. Starting at US$1, this bus is the most cost-effective option for your journey.
How much does the bus ticket cost from Charleston to St Louis?
The bus fare from Charleston to St Louis is approximately US$1.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston to St Louis was searched and found on Jun 20, 2025 with a price of US$128To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston to St Louis, as early as possible.
You can expect to pay from US$128 to US$138 for a bus ticket from Charleston to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$128 which is on 2025-06-20.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Charleston to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Charleston to St Louis, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to St Louis.
Tune out to the fine sounds of your best music playlist on your bus trip from Charleston to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Charleston to St Louis?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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