Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Baltimore Downtown Bus Station | Bus station | Cheapest | |||||
 | O'Donnell St. & Travel Plaza, Infront of TA Gas station | 2301 W Lucas St. | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | Baltimore Downtown Bus Station | Bus station | No tags | |||||
 | Baltimore Downtown Bus Station | Florence, SC | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Baltimore Bus Stop | Florence, SC | No tags |
Last refresh of the prices: Yesterday at 11:48 PM EDT.
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Compare 2 ways to go from Baltimore to Florence
Busbud recommends taking the train from Baltimore to FlorenceAmong the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 9 hours 12 minutes, and with fares starting at just US$83, it presents an excellent value for a comfortable ride.
Bus Baltimore to Florence, SC, US: Trip Overview
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Baltimore to Florence Bus
Busbud helps you find a bus from Baltimore to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Baltimore to Florence will be provided by the most trusted bus companies.
Discover how much the bus trip from Baltimore to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Baltimore and Florence?
Frequently asked questions on the trip Baltimore - Florence, SC, US
How much does a bus ticket from Baltimore to Florence cost?
The bus ticket price from Baltimore to Florence starts at US$48. The best way to find cheap bus tickets from Baltimore to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Baltimore to Florence?
The average travel time between Baltimore and Florence is around 10h 50m, although the fastest bus will take about 8h 50m.This is the time it takes to travel the 627 km that separates the two cities.
How many daily bus connections are there between Baltimore and Florence?
The number of buses from Baltimore to Florence can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Baltimore to Florence by comparing and selecting the bus that fits you travel style and budget on Busbud.
Which bus companies travel from Baltimore to Florence?
When taking the bus from Baltimore to Florence, you can travel comfortably and safely with FlixBus, Wanda Coach, Greyhound.
What are the departure and arrival stations when taking the bus from Baltimore to Florence?
Buses travelling between Baltimore and Florence leave from Baltimore Downtown Bus Station or Penn Station and arrive at Florence Bus Station, TA Travel Center - Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Baltimore to Florence, SC, US was searched and found on Oct 2, 2025 with a price of US$55To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, SC, US, as early as possible.
You can expect to pay from US$55 to US$100 for a bus ticket from Baltimore to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$55 which is on 2025-10-02.
Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Baltimore and Florence!
Much more than a mere vehicle taking you from Baltimore to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Baltimore to Florence will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Baltimore to Florence.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
What's the cheapest way to go from Baltimore to Florence, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular routes in this country
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