Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Avignon (Le Pontet) | Lyon - Perrache Bus Station | CheapestFastest | ||||
| Bus | Avignon (Le Pontet) | Lyon - Perrache Bus Station | No tags | ||||
 | Bus | Gare routière d'Avignon | Perrache | No tags | ||||
 | Bus | Avignon (Le Pontet) | Perrache | No tags | ||||
| Bus | Avignon (Le Pontet) | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Yesterday at 5:51 PM CET.
Compare 3 ways to go from Avignon to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 2 hours 20 minutes, and with fares starting at just $14, it presents an excellent value for a comfortable ride.
Where are the popular stops in Avignon and Lyon?
Stops in Avignon
- A
Gare Routière Avignon
54 Boulevard Saint-Roch, 84000 Avignon, France - B
Parking St. Bénézet
Boulevard du Rhône, 84000 Avignon, France - C
Avignon (TGV-Station)
Place de l'Europe, 84000 Avignon, France - D
Avignon (Bus Station)
42 Boulevard Saint-Roch, 84000 Avignon, France
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Avignon to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Avignon to Lyon?
The cheapest bus tickets from Avignon to Lyon start from $22. The average price for this route is around $38. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Avignon to Lyon?
The average bus travel time from Avignon to Lyon is 2h 45m, covering a distance of 199 km. The quickest bus can get you there in 1h 40m and is operated by BlaBlaCar Bus.
Which bus companies service the Avignon to Lyon route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, BlaBlaCar Bus, ALSA.
What are the earliest and latest departure times for the bus from Avignon to Lyon?
The earliest bus departs from Avignon to Lyon at 12:10am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Avignon to Lyon?
A bus trip from Avignon to Lyon generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Avignon to Lyon?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 60787 reviews.
Which bus company has the best Wi-Fi from Avignon to Lyon?
Based on Busbud reviews, the bus company ALSA has the highest Wi-Fi rating with a score of 3.5.
Which bus company has the best on-time performance from Avignon to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Avignon to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Avignon to Lyon was searched and found on Nov 30, 2025 with a price of $21To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Avignon to Lyon, as early as possible.
You can expect to pay from $21 to $101 for a bus ticket from Avignon to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $21 which is on 2025-11-30.
Usually ALSA, BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
