Train tickets from Spartanburg to Chicago

Previously seen trips

Next departures for Spartanburg to Chicago on November 17
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags

Compare 2 ways to go from Spartanburg to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 21 hours 50 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.

10bus per day
21h 50mAverage Duration
564 milesDistance
23kgCO₂ emissions
Average Price$77 - $302Average Duration21h 50m
23kg CO₂e
Average Price$189 - $1,255Average Duration1d 6h
83kg CO₂e

Frequently asked questions about traveling from Spartanburg to Chicago by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/15
$292
11/16
$199
Today
$379
11/18
No data
11/19
No data
11/20
No data
11/21
No data
11/22
No data
busbud logoThe cheapest trip from Spartanburg to Chicago was searched and found on Nov 16, 2025 with a price of $199

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Spartanburg to Chicago, as early as possible.

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