How much does a train ticket from Pittsburgh to St. Louis cost?

The average train ticket price from Pittsburgh to St. Louis is $161. The best way to find train tickets from Pittsburgh to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the train trip from Pittsburgh to St. Louis?

A train trip between Pittsburgh and St. Louis is around 23h 24m, although the fastest train will take about 20h 8m. This is the time it takes to travel the 557 miles that separates the two cities.

How many daily trains are there between Pittsburgh and St. Louis?

The number of trains from Pittsburgh to St. Louis can differ depending on the day of the week. On average, there are 2. Some trains are direct while others have layovers. Simplify your train trip from Pittsburgh to St. Louis by comparing and selecting the train that fits your travel style and budget on Busbud.

Which train companies travel from Pittsburgh to St. Louis?

When taking the train from Pittsburgh to St. Louis, you can travel comfortably and safely with Amtrak.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can explore the city. The top sights and things to do are Anheuser-Busch Brewery, Forest Park, Old St. Louis County Courthouse, Saint Louis Zoo, Gateway Arch.

Train Pittsburgh to St. Louis from $87 | Refundable Tickets

Previously seen trips

Next departures for Pittsburgh to St. Louis on November 15
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	11:59pm	Union Station	1d 1h	12:09am	Gateway Station	No tags
Train	11:59pm	Union Station	23h 24m	10:23pm	Gateway Station	No tags
Train	11:59pm	Union Station	20h 8m	7:07pm	Gateway Station	No tags
Train	11:59pm	Union Station	20h 8m	7:07pm	Gateway Station	No tags
Train	11:59pm	Union Station	1d 1h	12:09am	Gateway Station	No tags

Compare 2 ways to go from Pittsburgh to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 13 hours 35 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.

3bus per day

13h 35mAverage Duration

557 milesDistance

22kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$60 - $228	Average Duration13h 35m	CO₂ emissions 22kg CO₂e
Train	Average Price$80 - $927	Average Duration23h 24m	CO₂ emissions 82kg CO₂e

Train Companies

Amtrak

4/55,584 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5584 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $80

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Where are the popular train stations and stops in Pittsburgh and St. Louis?

Stops in Pittsburgh

A - Intermodal Station

Stops in St. Louis

A - Gateway Station

Frequently asked questions about traveling from Pittsburgh to St. Louis by train

How much does a train ticket from Pittsburgh to St. Louis cost?
How long is the train trip from Pittsburgh to St. Louis?
How many daily trains are there between Pittsburgh and St. Louis?
Which train companies travel from Pittsburgh to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/12

$188

11/13

$205

Today

$228

11/15

$109

11/16

$113

11/17

$97

11/18

$97

11/19

No data

The cheapest trip from Pittsburgh to St. Louis was searched and found on Nov 17, 2025 with a price of $97

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Pittsburgh to St. Louis, as early as possible.

You can expect to pay from $97 to $723 for a train ticket from Pittsburgh to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-11-17.