Train from Effingham to Greenville, SC: Tickets & Schedules

Previously seen trips

Next departures for Effingham to Greenville on November 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Effingham, IL
Greenville StationNo tags
AmtrakTrain
Effingham, IL
Greenville StationNo tags
AmtrakTrain
Effingham, IL
Greenville StationNo tags
AmtrakTrain
Effingham, IL
Greenville StationNo tags
AmtrakTrain
Effingham, IL
Greenville StationNo tags

Compare 2 ways to go from Effingham to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 19 hours 40 minutes and with fares starting at just $143, it presents an excellent value for a comfortable ride.

4bus per day
19h 40mAverage Duration
454 milesDistance
18kgCO₂ emissions
Average Price$143 - $160Average Duration19h 40m
18kg CO₂e
Average Price$277 - $408Average Duration1d 23h
66kg CO₂e

Frequently asked questions about traveling from Effingham to Greenville, SC by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Effingham to Greenville?

    The cheapest train tickets from Effingham to Greenville start from $277. The average price for this train route is around $346. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Effingham to Greenville?

    The average train ride duration from Effingham to Greenville is 1d 23h, covering a distance of 448 miles (722 km). The quickest train can get you there in 1d 23h and is operated by Amtrak.

  3. Which train operators service the Effingham to Greenville route?

    Several major train operators operate on this route with 1 trains available per day.

  4. What is the earliest and latest departure time for the train from Effingham to Greenville?

    The earliest train departs from Effingham to Greenville at 4:57am. And the latest train departs at 4:57am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/27
No data
11/28
No data
Today
$401
11/30
No data
12/01
No data
12/02
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12/03
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12/04
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busbud logoThe cheapest trip from Effingham to Greenville, SC was searched and found on Nov 29, 2025 with a price of $401

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Effingham to Greenville, SC, as early as possible.

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