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- This trip is recommended because it is: Cheapest + FastestDeparture time: June 24 atDeparture city: DurhamDeparture location: Durham StationArrival time: June 26 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: Amtrak
Vehicle: TrainDuration: - Departure time: June 24 atDeparture city: DurhamDeparture location: Durham StationArrival time: June 26 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 24 atDeparture city: DurhamDeparture location: Durham StationArrival time: June 26 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 24 atDeparture city: DurhamDeparture location: Durham StationArrival time: June 26 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: TrainDuration:
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Compare 2 ways to go from Durham to Chicago.
Busbud recommends taking the bus from Durham to ChicagoAmong the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours 20 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.
Train Durham to Chicago: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5229 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $211
Durham to Chicago Train
With Busbud, comparing and booking tickets for a train from Durham to Chicago is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make it our job to connect you with the most dependable companies that offer train service from Durham to Chicago.
From train tickets to high-end trains trip from Durham to Chicago, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Durham, NC, US - Chicago
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham to Chicago was searched and found on Jun 21, 2025 with a price of $322To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham to Chicago, as early as possible.
You can expect to pay from $322 to $1,820 for a train ticket from Durham to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $353 which is on 2025-06-24.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Durham to Chicago is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to Chicago, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Durham and Chicago compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Tune out to the fine sounds of your best music playlist on your train trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Traveled Train Routes
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Popular Trains Connecting Durham
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