How much is the train ticket from Cincinnati to St. Louis?

The cheapest train tickets from Cincinnati to St. Louis start from $93. The average price for this train route is around $160. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Cincinnati to St. Louis?

The average train ride duration from Cincinnati to St. Louis is 21h 42m, covering a distance of 306 miles (494 km). The quickest train can get you there in 18h 26m and is operated by Amtrak .

Which train operators service the Cincinnati to St. Louis route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the train from Cincinnati to St. Louis?

The earliest train departs from Cincinnati to St. Louis at 1:41am. And the latest train departs at 1:41am.

Train Cincinnati to St. Louis from $99 | Refundable Tickets

Next train departures

Next departures for Cincinnati to St. Louis on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	1:41am	Union Terminal	18h 26m	7:07pm	Gateway Station	CheapestFastest

Next departures for Cincinnati to St. Louis on December 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:41am	Union Terminal	21h 42m	10:23pm	Gateway Station	Cheapest
Train	1:41am	Union Terminal	18h 26m	7:07pm	Gateway Station	Fastest
Train	1:41am	Union Terminal	21h 42m	10:23pm	Gateway Station	No tags
Train	1:41am	Union Terminal	21h 42m	10:23pm	Gateway Station	No tags

Last refresh of the prices: Yesterday at 1:39 PM EST.

Compare 2 ways to go from Cincinnati to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 7 hours 25 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.

2bus per day

7h 25mAverage Duration

311 milesDistance

13kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$44 - $162	Average Duration7h 25m	CO₂ emissions 13kg CO₂e
Train	Average Price$93 - $639	Average Duration21h 42m	CO₂ emissions 45kg CO₂e

Train Companies

Amtrak

4/55,611 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5611 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $93

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Cincinnati to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Cincinnati to St. Louis?
The cheapest train tickets from Cincinnati to St. Louis start from $93. The average price for this train route is around $160. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Cincinnati to St. Louis?
The average train ride duration from Cincinnati to St. Louis is 21h 42m, covering a distance of 306 miles (494 km). The quickest train can get you there in 18h 26m and is operated by Amtrak.
Which train operators service the Cincinnati to St. Louis route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Cincinnati to St. Louis?
The earliest train departs from Cincinnati to St. Louis at 1:41am. And the latest train departs at 1:41am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/26

No data

11/27

$166

Today

No data

11/29

$909

11/30

No data

12/01

$220

12/02

No data

12/03

No data

The cheapest trip from Cincinnati to St. Louis was searched and found on Nov 27, 2025 with a price of $166

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Cincinnati to St. Louis, as early as possible.

You can expect to pay from $166 to $909 for a train ticket from Cincinnati to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $220 which is on 2025-12-01.