How much is the train ticket from San Diego to St. Louis?

The cheapest train tickets from San Diego to St. Louis start from $202. The average price for this train route is around $286. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from San Diego to St. Louis?

The average train ride duration from San Diego to St. Louis is 2d 6h, covering a distance of 1559 miles (2514 km). The quickest train can get you there in 1d 22h and is operated by Amtrak .

Which train operators service the San Diego to St. Louis route?

Several major train operators operate on this route with 4 trains available per day.

What is the earliest and latest departure time for the train from San Diego to St. Louis?

The earliest train departs from San Diego to St. Louis at 2:01pm. And the latest train departs at 4:10pm.

Train San Diego to St. Louis from $205 | Refundable Tickets

Next train departures

Next departures for San Diego to St. Louis on February 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	2:01pm	Santa Fe Depot	1d 22h	2:20pm	Gateway Station	Cheapest
Train	2:10pm	Old Town San Diego	1d 22h	2:20pm	Gateway Station	Fastest
Train	2:01pm	Santa Fe Depot	1d 22h	2:20pm	Gateway Station	No tags
Train	2:01pm	Santa Fe Depot	1d 22h	2:20pm	Gateway Station	No tags
Train	2:01pm	Santa Fe Depot	2d 6h	10:23pm	Gateway Station	No tags

Next departures for San Diego to St. Louis on March 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	2:01pm	Santa Fe Depot	1d 22h	2:20pm	Gateway Station	Cheapest
Train	2:10pm	Old Town San Diego	1d 22h	2:20pm	Gateway Station	Fastest
Train	4:01pm	Santa Fe Depot	2d 13h	7:30am	Gateway Station	No tags
Train	4:01pm	Santa Fe Depot	2d 13h	7:30am	Gateway Station	No tags
Train	4:01pm	Santa Fe Depot	2d 13h	7:30am	Gateway Station	No tags

Last refresh of the prices: Last Tuesday at 9:30 AM PST.

Compare 2 ways to go from San Diego to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 2 days, 40 minutes and with fares starting at just $137, it presents an excellent value for a comfortable ride.

14bus per day

2d Average Duration

1559 milesDistance

63kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$137 - $496	Average Duration2d	CO₂ emissions 63kg CO₂e
Train	Average Price$202 - $564	Average Duration2d 6h	CO₂ emissions 229kg CO₂e

Train Companies

Amtrak

4/55,762 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5762 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $202

US train companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from San Diego, CA, US to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from San Diego to St. Louis?
The cheapest train tickets from San Diego to St. Louis start from $202. The average price for this train route is around $286. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from San Diego to St. Louis?
The average train ride duration from San Diego to St. Louis is 2d 6h, covering a distance of 1559 miles (2514 km). The quickest train can get you there in 1d 22h and is operated by Amtrak.
Which train operators service the San Diego to St. Louis route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the train from San Diego to St. Louis?
The earliest train departs from San Diego to St. Louis at 2:01pm. And the latest train departs at 4:10pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

02/24

$275

02/25

$267

Today

$357

02/27

No data

02/28

$235

03/01

$266

03/02

No data

03/03

No data

The cheapest trip from San Diego, CA, US to St. Louis was searched and found on Feb 28, 2026 with a price of $235

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego, CA, US to St. Louis, as early as possible.

You can expect to pay from $235 to $2,083 for a train ticket from San Diego, CA, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $235 which is on 2026-02-28.