Bus Tickets from Wilmington, DE to Durham, NC, US

Find affordable bus tickets from Wilmington, DE to Durham, NC, US with flexible options. Book your trip now

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TodayAug 8
TomorrowAug 9
SunAug 10
from $79
MonAug 11
from $81
TueAug 12
from $78
WedAug 13
from $78
ThuAug 14
from $79
FriAug 15
from $82

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 10 at
    Departure city: Wilmington
    Departure location: Delaware Rest Stop S
    Arrival time: August 11 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 10 at
    Departure city: Wilmington
    Departure location: Wilmington Bus Station
    Arrival time: August 11 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Wilmington
    Departure location: Wilmington Bus Station
    Arrival time: August 10 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Wilmington
    Departure location: Wilmington Bus Station
    Arrival time: August 11 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Wilmington
    Departure location: Newark (DE)
    Arrival time: August 11 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Frequently asked questions for your trip Wilmington, DE - Durham, NC, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/06
$54
08/07
$80
Today
$49
08/09
No data
08/10
$72
08/11
$74
08/12
$84
08/13
$89
busbud logoThe cheapest trip from Wilmington, DE to Durham, NC, US was searched and found on Aug 8, 2025 with a price of $49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Durham, NC, US, as early as possible.

You can expect to pay from $49 to $106 for a bus ticket from Wilmington, DE to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $72 which is on 2025-08-10.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Wilmington to Durham.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Wilmington to Durham, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Wilmington to Durham will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Wilmington, DE by bus?

Bus from Wilmington, DE to Durham, NC, US

You can also go to Durham, NC, US by train

Train from Wilmington, DE to Durham, NC, US

Why choose Busbud?

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