Next departures for Syracuse to Buffalo on November 14
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Recommended
Price and booking link
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Next departures for Syracuse to Buffalo on November 15
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Recommended
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222 Waverly Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Next departures for Syracuse to Buffalo on November 16
Operated by
Vehicle type
Departure time
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Recommended
Price and booking link
Amtrak Station
Transportation Center
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Next departures for Syracuse to Buffalo on November 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
222 Waverly Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Next departures for Syracuse to Buffalo on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Next departures for Syracuse to Buffalo on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Amtrak Station
Transportation Center
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Next departures for Syracuse to Buffalo on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Amtrak Station
Transportation Center
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Next departures for Syracuse to Buffalo on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
222 Waverly Ave
Buffalo Niagara International Airport, (Arrivals) Bus parking area
Cheapest
Syracuse (Regional Transportation Center)
Buffalo (BUF) Airport
Fastest
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
Syracuse (Regional Transportation Center)
Niagara Frontier Transportation Authority
No tags
SYR Airport
Depew Station
No tags
Last refresh of the prices: Today at 5:50 AM EST.
Compare 2 ways to go from Syracuse to Buffalo
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 2 hours 32 minutes and with fares starting at just $30, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
With about 1 daily trips between Syracuse and Buffalo, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
OurBus Syracuse Buffalo recent customer reviews
The bus showed up late and arrived in Buffalo over an our late but it wasn't the bus drivers fault. Traffic was very very slow. The bus was well cooled and comfortable. The wifi would connect but nothing would ever load so I had to use my cell data but that's alright. Overall my experience with Ourbus was very good and if I need to go somewhere again I will be using Ourbus!
Based on 5584 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $43
Amtrak Syracuse Buffalo recent customer reviews
train was delayed multiple times with no real explanation given
Based on 1124 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the cleanliness but often complained with the wifi. Adirondack Trailways ticket prices on this trip start at $73
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
Frequently asked questions about traveling from Syracuse, US to Buffalo, NY by bus
What is the travel distance from Syracuse to Buffalo?
The distance separating Syracuse and Buffalo is 139 miles (224 km).
What are the departure and arrival stations when taking the bus from Syracuse to Buffalo?
The majority of buses traveling from Syracuse to Buffalo start their journey at Regional Transportation Center and wind up at Transportation Center. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/12
$27
11/13
$28
Today
$22
11/15
$22
11/16
$25
11/17
$22
11/18
$24
11/19
$25
The cheapest trip from Syracuse, US to Buffalo, NY was searched and found on Nov 14, 2025 with a price of $22
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Buffalo, NY, as early as possible.
You can expect to pay from $22 to $109 for a bus ticket from Syracuse, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $22 which is on 2025-11-15.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.